Neutrophil-to-Lymphocyte Ratio (NLR) as An Inflammation Degree Marker in Tongue Cancer Patient

Jurnal Kesehatan Gigi

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Field Value
 
Title Neutrophil-to-Lymphocyte Ratio (NLR) as An Inflammation Degree Marker in Tongue Cancer Patient
 
Creator Lathifah, Syakira Husna
Yohana, Winny
Rodian, Moch.
 
Subject neutrophil-to-lymphocyte ratio; inflammation degree; tongue cancer; prognosis
 
Description Tongue cancer is one of the most common malignancies of all oral malignancies. Cancer staging is induced by a systemic inflammatory response with one of the markers, one of them is neutrophil-lymphocyte ratio (NLR). This study aims to provide an overview of the NLR as a marker of the degree of inflammation in patients with tongue cancer. This systematic literature review was conducted online from January 2021 to March 2021 against articles reporting RNL as a marker of inflammatory action in patients with tongue cancer. The search for articles referred to Preferred Reporting Items for Systematic Review and Meta-analysis (PRISMA) and conducted through PubMed, PMC, ScienceDirect, and EBSCOhost with the publication year 2015-2020. Selected articles met the criteria according to the PICO framework (Population, Intervention, Comparison, Outcome). Article screening is done by reading the title and abstract, checking for duplication, and reading the entire text. Sixteen in 841 research articles with observational study design were identified, the NLR cut-off value ranges from 2.04-2.95. Nine in ten research articles suggested a relationship between the NLR value and several clinicopathological characteristics of the patient. Twelve articles mentioned that there was the association of RNL with patient overall survival (OS), disease-free survival (DFS), and disease-specific survival (DSS). The NLR value can be an indicator of the degree of inflammation in patients with tongue cancer as assessed from the parameters of the clinicopathological assessment and can be a predictive factor for patient's prognosis or survival status.
 
Publisher Jurusan Keperawatan Gigi, Poltekkes Kemenkes Semarang
 
Contributor Endang Sjamsudin, Universitas Padjadjaran, Departement of Oral and Maxillofacial Surgery
Jamas Ari Anggraini, Universitas Padjadjaran, Departement of Oral Biology
Erna Herawati, Universitas Padjadjaran, Departement of Oral Medicine
 
Date 2021-12-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://ejournal.poltekkes-smg.ac.id/ojs/index.php/jkg/article/view/7024
10.31983/jkg.v8i2.7024
 
Source Jurnal Kesehatan Gigi; Vol 8, No 2 (2021): Desember 2021; 96-108
2621-3664
2407-0866
 
Language eng
 
Relation https://ejournal.poltekkes-smg.ac.id/ojs/index.php/jkg/article/view/7024/2431
https://ejournal.poltekkes-smg.ac.id/ojs/index.php/jkg/article/downloadSuppFile/7024/6176
 
Rights Copyright (c) 2021 Jurnal Kesehatan Gigi
 

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