Synthesis and Antimicrobial Activity of New Benzimidazole derivatives Bearing Five-Membered Heterocyclic Moieties

Al-Mustansiriyah Journal of Science

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Field Value
 
Title Synthesis and Antimicrobial Activity of New Benzimidazole derivatives Bearing Five-Membered Heterocyclic Moieties
 
Creator Abbood, Ammar Ferman
Abdula, Ahmed M.
Mohsen, Ghosoun Laftaa
Baqi, Younis
 
Subject
benzimidazol, pyrazoline, isoxazoline, antimicrobial
 
Description A new series of 2-substituted-1H-benzimidazol as potentially antimicrobial agents were designed, synthesized and characterized by IR, 1H-NMR and Mass spectra. The synthesized compounds were in vitro screened against Escherichia coli, Klebsiella spp. (gram negative), Staphylococcus aureus, Staphylococcus epidermidis (gram positive) as well as Candida albicans. The in vitro biological evaluation revealed that some of the target compounds exerted good antimicrobial activity. Noticeably, compound 11 exhibited promising activity against Staphylococcus aureus and Klebseilla SPP at 1 mg/mL concentration.
 
Publisher Mustansiriyah University
 
Contributor
 
Date 2021-11-20
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/992
10.23851/mjs.v32i4.992
 
Source Al-Mustansiriyah Journal of Science; Vol 32, No 4 (2021); 26-33
2521-3520
1814-635X
10.23851/mjs.v32i4
 
Language eng
 
Relation http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/992/pdf
 
Rights Copyright (c) 2021 Al-Mustansiriyah Journal of Science
http://creativecommons.org/licenses/by-nc/4.0
 

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