Synthesis and Antimicrobial Activity of New Benzimidazole derivatives Bearing Five-Membered Heterocyclic Moieties
Al-Mustansiriyah Journal of Science
View Publication Info| Field | Value | |
| Title |
Synthesis and Antimicrobial Activity of New Benzimidazole derivatives Bearing Five-Membered Heterocyclic Moieties
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| Creator |
Abbood, Ammar Ferman
Abdula, Ahmed M. Mohsen, Ghosoun Laftaa Baqi, Younis |
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| Subject |
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benzimidazol, pyrazoline, isoxazoline, antimicrobial |
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| Description |
A new series of 2-substituted-1H-benzimidazol as potentially antimicrobial agents were designed, synthesized and characterized by IR, 1H-NMR and Mass spectra. The synthesized compounds were in vitro screened against Escherichia coli, Klebsiella spp. (gram negative), Staphylococcus aureus, Staphylococcus epidermidis (gram positive) as well as Candida albicans. The in vitro biological evaluation revealed that some of the target compounds exerted good antimicrobial activity. Noticeably, compound 11 exhibited promising activity against Staphylococcus aureus and Klebseilla SPP at 1 mg/mL concentration.
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| Publisher |
Mustansiriyah University
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| Contributor |
—
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| Date |
2021-11-20
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
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| Format |
application/pdf
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| Identifier |
http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/992
10.23851/mjs.v32i4.992 |
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| Source |
Al-Mustansiriyah Journal of Science; Vol 32, No 4 (2021); 26-33
2521-3520 1814-635X 10.23851/mjs.v32i4 |
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| Language |
eng
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| Relation |
http://mjs.uomustansiriyah.edu.iq/ojs1/index.php/MJS/article/view/992/pdf
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| Rights |
Copyright (c) 2021 Al-Mustansiriyah Journal of Science
http://creativecommons.org/licenses/by-nc/4.0 |
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