PREVALENCE OF TOXOPLASMA GONDII IGG AND IGM AND ASSOCIATED RISK FACTORS AMONG HIV-POSITIVE AND HIV-NEGATIVE PATIENTS IN VHEMBE DISTRICT OF SOUTH AFRICA

African Journal of Infectious Diseases (AJID)

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Title PREVALENCE OF TOXOPLASMA GONDII IGG AND IGM AND ASSOCIATED RISK FACTORS AMONG HIV-POSITIVE AND HIV-NEGATIVE PATIENTS IN VHEMBE DISTRICT OF SOUTH AFRICA
 
Creator Ngobeni, Renay
Samie, Amidou
 
Subject Tradtional Medicine, Medicinal Plants
ELISA, HIV, Toxoplasma gondii, Sero-prevalence, Opportunistic infections.
 
Description Background: Toxoplasma gondii is a zoonotic parasite that has arisen as an important opportunistic infection that causes
morbidity and mortality especially in HIV positive patients. This study was carried out to determine the sero-prevalence of
T. gondii (IgG and IgM) and the associated risk factors among HIV positive and negative patients in Northern South Africa.
Materials and Methods: The study was conducted in the Vhembe District in Limpopo province from April 2012 to
January 2013. A well-structured questionnaire was used to collect socio-demographic information and possible risk factor
information on toxoplasmosis from participants. A total of 161 blood samples of both HIV positive and negative patients
visiting the local clinics in the Vhembe district were collected. Serum samples were tested for IgG and IgM against T.
gondii using commercially available ELISA protocol.
Results: The prevalence of T. gondii IgG was 31.7% while that of T. gondii IgM was 4.9%. The prevalence of T. gondii
IgG was higher in HIV positive patients (38%) compared to 16.7% among HIV negative patients (p=0.001). Toxoplasma
gondii IgG antibodies were more common in patients who were not taking ARV’s (46.2%) compared to those who were
taking ARV’s (35.2%) (P25 years).
 
Publisher African Traditional Medicine Supporters Initiative (ATHMSI), 7, Road 1, Otunmaiye Square
 
Contributor hospital management and the patients for their cooperation throughout the study.
 
Date 2017-06-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://journals.sfu.ca/africanem/index.php/AJID/article/view/4784
10.21010/ajid.v11i2.1
 
Source African Journal of Infectious Diseases (AJID); Vol 11, No 2 (2017); 1-9
2505-0419
2006-0165
 
Language eng
 
Relation http://journals.sfu.ca/africanem/index.php/AJID/article/view/4784/2988
 
Coverage Africa


 
Rights Copyright (c) 2017 African Journal of Infectious Diseases (AJID)
 

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