Synthesis and Antibacterial Property of An Encapsulated Sulfonamide Nanoparticle in a Multidisciplinary Approach

International Journal for Innovation Education and Research

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Field Value
 
Title Synthesis and Antibacterial Property of An Encapsulated Sulfonamide Nanoparticle in a Multidisciplinary Approach
 
Creator Brown, Ashli
Fernandez, Mercedes
Parker, Shaquan
Whitfield, ZeAndra D.
Zheng , Xiaomei
Mandouma, Ghislain R
 
Subject Nanoparticle
Multidisciplinary
Dendrimer
Antibiotic
Sulfonamide
 
Description Multigram quantity of a novel Sulfa Drug complex -poly(amido)amine-sulfonamide or PAMAM-Sulfa- was synthesized, from commercially available materials. It was characterized with spectroscopic methods such as nuclear magnetic resonance (NMR). The Kirby-Bauer test was used to test it against gram positive and/or gram negative bacteria using different concentrations of an ethanol solution of the PAMAM-Sulfa complex. The goal of this experiment was to synthesize and study the effect of water soluble encapsulated sulfonamides on common bacteria by undergraduate students engaging in research involving more than one STEM discipline. Students synthesized a dendrimer-sulfonamide complex before evaluating its antibiotic properties. In doing so, students employed research methods that are common to chemistry, biology and nanoscience while also learning about mechanism of infectious diseases, drugs and drug resistance. This project allowed students to combine aspects of scientific research that are usually done separately, and an opportunity to observe the seamlessness of multidisciplinary science.
 
Publisher International Educative Research Foundation Publisher (IERFP)
 
Date 2021-09-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://ijier.net/ijier/article/view/3322
10.31686/ijier.vol9.iss9.3322
 
Source International Journal for Innovation Education and Research; Vol. 9 No. 9 (2021): International Journal for Innovation Education and Research; 151-157
2411-2933
2411-3123
 
Language eng
 
Relation https://ijier.net/ijier/article/view/3322/2268
 
Rights Copyright (c) 2021 Ashli Brown, Mercedes Fernandez, Shaquan Parker, ZeAndra D. Whitfield, Xiaomei Zheng , Ghislain R Mandouma
https://creativecommons.org/licenses/by-nd/4.0
 

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