Calorie Restriction, Stem Cells, and Rejuvenation Approach

Sains Medika

View Publication Info
 
 
Field Value
 
Title Calorie Restriction, Stem Cells, and Rejuvenation Approach
 
Creator Nasihun, Taufiqurrachman
 
Subject Calorie Restriction; Stem Cenation Approachells; and Rejuv
 
Description Aging may be defined as the time-dependent deterioration in function of an organism associated with or responsible for the increase in susceptibility to disease and probability of death with advancing age (Harman, 1981; Cefalu, 2011). Generally, the aging organisms are characterized by both biochemical and functional declines. Declining of basal metabolism rates, protein turnover, glucose tolerance, reproductive capacity, telomere shortening, and oxidative phosphorylation are related to the biochemical. Whilst, lung expansion volume, renal glomerular and tubular capacities, cardiovascular performance, musculoskeletal system, nerve conduction velocity, endocrine and exocrine systems, immunological defenses, and sensory systems are associated with the physiological declining (Baynes and Dominiczak, 2015). Some evidences indicated that, although members of a species develop into adults in the same way, even genetically similar or identical individuals, raised in identical conditions and eating identical food, but they may age differently (Baynes and Dominiczak, 2015). These aging differences are attributable to the life style particularly calorie and dietary restriction intakes, reactive oxygen species (ROS) production, and thus its implication on severity of damage, repair capacity, and error accumulation in cellular genetic material (Baynes and Dominiczak, 2015; Mihaylova et al., 2014; Mazzoccoli et al., 2014). Therefore, in molecular terms, aging can be defined as a decline of the homeostatic mechanisms that ensure the function of cells, tissues, and organs systems (Mazzoccoli et al., 2014). Accordingly, if the homeostatic mechanism can be repaired, the result is rejuvenation.
 
Publisher Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)
 
Contributor
 
Date 2017-03-09
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1171
 
Source Sains Medika; Vol 7, No 2 (2016): July-December 2016; 40-42
2339-093X
2085-1545
 
Language eng
 
Relation http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/1171/904
 
Rights Copyright (c) 2017 Taufiqurrachman Nasihun
http://creativecommons.org/licenses/by/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2016 Simon Fraser University Library