Intravenous Dexamethasone versus Tramadol for Prevention of Shivering after General Anaesthesia: A Randomised Double Blind Placebo Controlled Trial

Academia Anesthesiologica International

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Title Intravenous Dexamethasone versus Tramadol for Prevention of Shivering after General Anaesthesia: A Randomised Double Blind Placebo Controlled Trial
 
Creator Chauhan, Jainendra
R. S. Rautela
Rashmi Salhotra
Das, Nilima
 
Subject Dexamethasone
tramadol hydrochloride
anaesthesia
general
shivering
postoperative nausea and vomiting
 
Description Background: Postoperative shivering is very common and followed by many complications. In most operating and recovery rooms, shivering is controlled by the use of humidifiers, warming blankets and humidified oxygen. However pharmacological control is an alternative modality. The goal of this study was to compare the effect of dexamethasone, tramadol and saline for prevention of shivering and nausea/vomiting after general anaesthesia. Subjects and Methods: This double blind randomised controlled study was carried out on 300 patients being operated under general anaesthesia. The patients were block randomised into three groups (n=100 each). Group D received 0.1 mg.kg−1dexamethasone, Group T received 1 mg.kg−1tramadol and Group C received normal saline I.V as 10 ml solution just after endotracheal intubation. Temperature monitoring was done. In the recovery room, all patients were continuously observed for occurrence of shivering, nausea and vomiting. Quan- titative parameters were compared by unpaired t-test and qualitative parameters by Chi-square / Fisher’s exact test. Hemodynamic parameters were compared using repeated measure ANOVA. Results: The incidence of shivering was 23% in group D, 9% in group T and 51% in group C (p<0.001). In group D, 22% patients developed PONV as compared to 62% in group T and 59% in group C (p<0.001). Conclusion: Both dexamethasone and tramadol are effective anti-shivering agents with tramadol being more effective. However, since tramadol has a slightly higher clinical incidence of nausea/vomiting, dexamethasone should be the preferred anti-shivering agent in surgeries or patient subgroup who are at a higher risk of developing PONV.
 
Publisher Society for Health Care & Research Development
 
Date 2021-06-17
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
application/xml
text/html
application/epub+zip
 
Identifier https://aijournals.com/index.php/aan/article/view/1965
 
Source Academia Anesthesiologica International; Vol 6 No 1 (2021): January-June 2021; 118-124
2456-7388
2617-5479
 
Language eng
 
Relation https://aijournals.com/index.php/aan/article/view/1965/2332
https://aijournals.com/index.php/aan/article/view/1965/2333
https://aijournals.com/index.php/aan/article/view/1965/2334
https://aijournals.com/index.php/aan/article/view/1965/2335
 
Rights Copyright (c) 2021 Author
https://creativecommons.org/licenses/by/4.0/
 

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