Evaluation of the Efficacy and Safety of Dexmedetomidine versus Propofol for Sedation in Children Undergoing MRI

Academia Anesthesiologica International

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Title Evaluation of the Efficacy and Safety of Dexmedetomidine versus Propofol for Sedation in Children Undergoing MRI
Creator Khushboo Bhavsar
Naynaben Vaghani
Annirudh Gadhavi
Naval, Rajesh
Subject Dexmedetomidine
Recovery time
Description Background: The present research was performed to assess the efficacy and safety of dexmedetomidine versus propofol for sedation in children endures MRI. Subjects and Method: This prospective randomized research was performed in the Department of Anaesthesia at Medical College, Surendranagar. Baseline HR, systolic blood pressure (SBP), respiratory rate (RR), and oxygen saturation (SpO2) Onset of sedation were documentated on entrance to the research room. Children were divided in dexmedetomidine (Group D) or propofol (Group P). Group D (n= 30) received injection dexmedetomidine1µg/kg for 10 min trailed by constant Dexmedetomidine 0.5-0.7µg/kg/h. Group P (n = 30) received injection propofol 1 mg/kg bolus trailed by constant infusion of 100 µg/kg/min. Site and duration of MRI, onset of sedation (RSS = 5), duration of sedation, incremental infusion requirement, and recovery time were recorded. Results: Mean age, weight, and sex ratio among the two groups were comparable. The mean time to attain the requisite level of sedation was comparable in both the groups The utilization of Dexmedetomidine for postoperative analgesia consequences in considerably fewer added pain medication and sluggish heart rates than a control group. Conclusion: Dexmedetomidine is analogous with propofol as maintenance anesthetic agent and it can create improved organize of hemodynamic erratics. Propofol has a benefit of given that quick onset of sedation and faster revival instance.
Publisher Society for Health Care & Research Development
Date 2021-06-05
Type info:eu-repo/semantics/article
Format application/pdf
Identifier https://aijournals.com/index.php/aan/article/view/1955
Source Academia Anesthesiologica International; Vol 6 No 1 (2021): January-June 2021; 101-105
Language eng
Relation https://aijournals.com/index.php/aan/article/view/1955/2300
Rights Copyright (c) 2021 Author

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