The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum

Sains Medika

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Title The Antifungal Effect of Kesum Leaf (Polygonum minus Huds) in Ethanol Extract on Microsporum gypseum
 
Creator Liauw, Josephine Johan
Rizki, Syarifah Nurulyanti
Natalia, Diana
Mahyarudin, Mahyarudin
 
Subject Antifungal; ethanol extract of kesum leaves (Polygonum minus Huds); Microsporum gypseum
 
Description Introduction: Dermatophytosis or tinea is a disease found in the keratinized tissues caused by dermatophytes. The prolonged use of antifungal drugs has adverse effects on humans. Kesum leaves (Polygonum minus Huds) contains the secondary metabolite properties which can act as anti-fungi. Objective: This study aimed to determine the antifungal activity of ethanol extract of kesum leaves in inhibiting the Microsporum gypseum.Methods: Phytochemical analysis was performed using a test tube method and thin layer chromatography. The antifungal activity test used a disc diffusion method with the extract concentrations of 5%, 10%, 20%, 40%, and 80%. Kesum leaves macerated using ethanol 96% solvent. Itraconazole 8µl/disk and DMSO4 were respectively used as positive and negative control. Results: Phytochemical analysis on the ethanol extract of kesum leaves showed the secondary metabolite groups of flavonoids, alkaloids, terpenoids, phenolics, and saponins. Ethanol extract of kesum leaves did not form an inhibitory zone on the growth of Microsporum gypseum. Meanwhile in the positive control, in the form of itraconazole 8 µl/disk, the inhibition zone was formed around the disc with a mean value of 37.5 mm.Conclusion: Ethanol extract of kesum leaves (Polygonum minus Huds) has no antifungal activity against the growth of Microsporum gypseum.
 
Publisher Fakultas Kedokteran; Universitas Islam Sultan Agung (UNISSULA)
 
Contributor
 
Date 2021-05-03
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/4448
10.30659/sainsmed.v12i1.4448
 
Source Sains Medika: Jurnal Kedokteran dan Kesehatan; Vol 12, No 1 (2021): January - June 2021; 26-33
2339-093X
2085-1545
10.30659/sainsmed.v12i1
 
Language eng
 
Relation http://jurnal.unissula.ac.id/index.php/sainsmedika/article/view/4448/pdf
 
Rights Copyright (c) 2021 Sains Medika: Jurnal Kedokteran dan Kesehatan
 

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