High antioxidant level in cajanus sajan reduces blood glucose level and improves blood lipid profile of rats as diabetes mellitus models

International Journal of Health Sciences

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Title High antioxidant level in cajanus sajan reduces blood glucose level and improves blood lipid profile of rats as diabetes mellitus models
 
Creator Laraeni, Yuli
Danuyanti, I Gusti Ayu Nyoman
Resnhaleksmana, Ersandhi
Pauzi, Iswari
Mataram, I Komang Agusjaya
Agustini, Ni Putu
 
Subject blood glucose
cholesterol
lipid profile
pigeon bean tempe
triglycerides
 
Description Hyperglycemia in DM was able to increase glucose auto-oxidation, protein glycation, and polyol pathway activation. As a result, it can accelerate the formation of reactive oxygen compounds acting as the main factor causing DM complication. Prior to our evaluation of pigeon bean Tempe with formulations of 25%, 50% and 75%, we tested the number and activity of its antioxidant. Then we substituted it on standard feed for 14 days to find the effects on glucose level and lipid profile. The effects was then compared to that before the intervention. The result showed that the total and activity of antioxidant in pigeon bean Tempe (Cajanus sajan) was 15% and 41.30% respectively. On the other side, pigeon bean Tempe with a formulation of 75% was more able to reduce blood glucose level, total cholesterol, triglycerides, and LDL-cholesterol by 44.08%, 34.38%,35.80%, and 43.22% respectively (p<0.05) if compared to pigeon bean Tempe with formulations of 25% and 50%. Meanwhile pigeon bean Tempe with formulation of 75% provided better effects for an increase of HDL level 56.20% (p<0.05). All test results on Tempe formulation used were compared to that before intervention.
 
Publisher Universidad Tecnica de Manabi
 
Date 2021-01-25
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Identifier http://sciencescholar.us/journal/index.php/ijhs/article/view/725
10.29332/ijhs.v5n1.725
 
Source International journal of health sciences; Vol. 5 No. 1 (2021): Online First
2550-696X
2550-6978
 
Rights Copyright (c) 2021 International journal of health sciences
http://creativecommons.org/licenses/by-nc-nd/4.0
 

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