Hepatitis A

Medicina y Laboratorio

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Title Hepatitis A
Hepatitis A
Creator Restrepo Gutiérrez, Juan Carlos
Toro Montoya, Ana Isabel
Subject hepatitis A, hepatitis A virus, HAV, clinical manifestations, diagnosis, epidemiology, pathogenesis, prevention.
hepatitis A, virus de la hepatitis A, VHA, clínica, diagnóstico, epidemiología, patogénesis, prevención.
Description Hepatitis caused by hepatitis A virus is an acute disease, quite common at a worldwide leve. Although it remains endemic in developing countries, the seroprevalence rates in developed countries continue to decline. In children, the acute infection is usually asymptomatic, but in adults it may present with a variety of clinical manifestations ranging from mild to fulminant liver failure, which fortunately is very rare. The virus is usually transmitted by ingestion of food and water contaminated with feces infected with the virus. The diagnosis of hepatitis A is based on laboratory tests, supported by the search for IgM antibodies specific for hepatitis A virus. Immunoprophylaxis with anti-HAV gamma globulin can prevent and mitigate the disease in people exposed to the virus. On the other side, the vaccine induces long-term immunity and opens the possibility to eradicate this disease from the world.
La hepatitis causada por el virus de la hepatitis A es una enfermedad aguda, frecuente a nivel mundial. Aunque permanece endémica en países en desarrollo, las tasas de seroprevalencia en los países desarrollados continúan disminuyendo. En los niños la infección aguda usualmente es asintomática; sin embargo, en los adultos se pueden presentar una variedad de manifestaciones clínicas que van desde leves hasta una falla hepática fulminante, la cual afortunadamente, es muy poco frecuente. La transmisión de virus es generalmente por la ingestión de agua y alimentos contaminados con materia fecal que está infectada con el virus. El diagnóstico de la  hepatitis A se basa en las pruebas de laboratorio, apoyadas en la búsqueda de anticuerpos tipo IgM, específicos para el virus de la hepatitis A. La inmunoprofilaxis con gamma globulina anti-VHA puede prevenir y atenuar la enfermedad en personas expuestas al virus. La vacuna por su parte, induce inmunidad a largo plazo y abre la posibilidad a la erradicación de esta enfermedad en el mundo.
Publisher EDIMECO S.A.
Date 2011-01-01
Type info:eu-repo/semantics/article
Format application/pdf
Identifier https://medicinaylaboratorio.com/index.php/myl/article/view/320
Source Medicina & Laboratorio; Vol. 17 No. 1-2 (2011); 11-22
Medicina y Laboratorio; Vol. 17 Núm. 1-2 (2011); 11-22
Language spa
Relation https://medicinaylaboratorio.com/index.php/myl/article/view/320/308
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