HUBUNGAN KADAR UREA DENGAN HOMOCITRULINE PADA GAGAL GINJAL TERMINAL

Majalah Kedokteran Andalas

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Title HUBUNGAN KADAR UREA DENGAN HOMOCITRULINE PADA GAGAL GINJAL TERMINAL
 
Creator Rifnayeni, Verbrini
Nasrul, Ellyza
Maani, Hanifah
Rofinda, Zelly Dia
 
Subject urea; homocitruline; gagal ginjal terminal; urea; homocitruline; end stage renal disease
 
Description AbstrakPeningkatan kadar urea (uremia) ditemukan pada gagal ginjal terminal.Tujuan penelitian ini adalah untuk mengetahui hubungan kadar urea dengan homocitruline pada pasien gagal ginjal terminal. Penelitian ini menggunakan rancangan analitik observasional cross sectional pada 23 pasien gagal ginjal terminal yang menjalani Hemodialisis di RSUP. Dr. M. Djamil Padang. Penelitian berlangsung sejak Februari hingga Oktober 2014. Subjek diambil dengan consecutive sampling. Sampel serum diperiksa kadar ureanya dengan metode enzimatik glutamate dehidrogenase. Homocitruline diperiksa secara indirek ELISA. Analisis statistik menggunakan uji korelasi Pearson. Hasil penelitian ini menunjukkan jumlah subjek sebanyak 52,2% perempuan dan 47,8 % laki-laki, dengan rerata umur 48,6+10,6 tahun, kadar urea 102,1+26,0 mg/dL, kadar homocitruline 1,2+0,7 ng/mL. Penelitian ini menunjukan ada korelasi negatif yang tidak signifikan (r=-0.2, p > 0.05) antara kadar urea dengan homocitruline pada pasien gagal ginjal terminal.AbstractIncrease urea (uremia) can be found at end stage renal disease. This study was know correlation between urea with homocitruline level at end stage renal disease. This is cross sectional observational analytic study at 23 patients with end stage renal disease on hemodyalisis in M. Djamil Hospital, Padang, from February 2014 until October 2014, with consecutive sampling. Urea level was determined from serum sample by kinetic enzymatic glutamate dehydrogenase, and homocitruline by indirect ELISA. Statistical analysis was done by pearson correlation. The research showed that 52.2% are women and 47.8% are men with mean age is 48.6+10.6 years old, mean urea level is 102.1+26.0 mg/dL, homocitruline level is 1.2+0.7 ng/mL. The correlation between urea level and homocitruline was not significant (r=-0.2, p > 0.05). There was negative weak correlation between urea level and homocitruline at end stage renal disease.
 
Publisher Faculty of Medicine Andalas University
 
Contributor
 
Date 2015-12-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://jurnalmka.fk.unand.ac.id/index.php/art/article/view/298
10.22338/mka.v38i2.298
 
Source Majalah Kedokteran Andalas; Vol 38, No.2, AGUSTUS 2015; 124-129
2442-5230
0126-2092
 
Language eng
 
Relation http://jurnalmka.fk.unand.ac.id/index.php/art/article/view/298/240
 
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