Estimated glomerular filtration rate function in patients with and without metabolic syndrome

Revista Facultad de Ciencias de la Salud UDES

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Title Estimated glomerular filtration rate function in patients with and without metabolic syndrome
Estimación de la tasa de filtración glomerular en personas con y sin síndrome metabólico
 
Creator Lizardo, María E
Navarro, María del Pilar
Camacho, Marqjuly
Magallanes-Hernández, Melvimar Alejandra
Pacheco-Gutiérrez, Rubsy Gabriela
López-Bordones, Mariela
Cabello, Román
González-Mayo, Gregoria
Vicci, Hember
Dorta, Luis
 
Subject Metabolic syndrome x; glomerular filtration rate; obesity; hypertension; renal insufficiency, chronic
Síndrome X Metabólico; tasa de filtración glomerular; obesidad; hipertensión; insuficiencia renal crónica
 
Description Introduction: Metabolic syndrome (MS) is an independent risk factor, which affects the development of chronic kidney disease, so the glomerular filtration rate (GFR) as an indicator of glomerular function in patients with and without MS who attended the outpatient clinic “los Grillitos, sector Caña de Azucar”. Materials and Methods: A comparative, correlational, cross-sectional study was conducted in a non-probability sample of convenience consisting of 60 patients with MS diagnosed according to the criteria Panel ATP III, and 60 apparently healthy individuals, whom the GFR was determined by the Cockcroft-Gault as well as clinical and biochemical parameters for the diagnosis of MS. Results: Out of the total patients evaluated, 37 (30.7%) showed alterations that put them in grades G2 and G3 system risk stratification of CKD, of these 18 and 19 corresponded to patients with and without MS respectively. Glomerular Hyperfiltration (> 120 mil / min) it was found in both groups 28 (46.7%) and 24 (40%) cases of patients with and without MS respectively. The glomerular function was strongly correlated with abdominal obesity and high levels of stress arterial. As for the number of criteria and its relationship to the level of kidney damage present, not a firm to increase the latter with respect to the first (p=0.385) trend was observed. Conclusion: The change in the glomerular function is not directly related to the MS but with its components, specifically abdominal obesity and hypertension.
Introducción: El Síndrome Metabólico(SM) es un factor de riesgo independiente, que incide en el desarrollo de enfermedad renal crónica (ERC),  se estimó la tasa de filtración glomerular como indicador de la Función Glomerular (FG) en pacientes con y sin SM que asistieron al ambulatorio Los Grillitos, sector Caña de Azúcar. Materiales y métodos: se realizó un estudio comparativo, correlacional, transversal en una muestra no probabilística por conveniencia conformada por 60 pacientes con SM diagnosticados según los criterios del Panel de la ATP III, y 60 individuos aparentemente sanos, a quienes se determinó la FG mediante la ecuación de Cockcroft-Gault así como los parámetros clínicos y bioquímicos para el diagnóstico del SM. Resultados: del total de pacientes evaluados, 37 (30,7%) mostraron alteraciones que los ubican en los grados G2 y G3 del sistema de estratificación de riesgo de ERC, de estos 18 y 19 correspondían a los pacientes con y sin SM respectivamente. Se encontró hiperfiltración glomerular (>120 mil/min) en ambos grupos 28 (46,7%) y 24 (40%) casos de pacientes con y sin SM respectivamente La función glomerular se correlacionó fuertemente con la obesidad abdominal y niveles elevados de tensión arterial. En cuanto al número de criterios y su relación con el nivel de daño renal presente, no se observó una tendencia firme al incremento del último con respecto del primero (p 0,385). Conclusión: La alteración en la función glomerular no está relacionada directamente con el SM pero si con sus componentes, específicamente con la obesidad abdominal y la hipertensión arterial.
 
Publisher Universidad de Santander (UDES)
 
Contributor

 
Date 2016-06-30
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Original Article

 
Format application/pdf
 
Identifier https://journalhealthsciences.com/index.php/UDES/article/view/99
10.20320/rfcsudes.v3i1.102
 
Source Revista Facultad de Ciencias de la Salud UDES; Vol. 3, Núm. 1 (2016); 22-28
Revista Facultad de Ciencias de la Salud UDES; Vol. 3, Núm. 1 (2016); 22-28
2422-1074
2422-1074
 
Language spa
 
Relation https://journalhealthsciences.com/index.php/UDES/article/view/99/O.2%20Lizardo
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