Echinocandins for candidemia: a rational choice

Reviews in Health Care

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Field Value
Title Echinocandins for candidemia: a rational choice
Creator Menichetti, Francesco
Tagliaferri, Enrico
Subject Clinical Medicine
Echinocandins; Candidemia; Invasive candidiasis
Description Among antifungal drugs, echinocandins (micafungin, caspofungin and anidulafungin) represent a rational choice for the first-line therapy of candidemia/invasive candidiasis in critically ill patients. Among other properties characterizing echinocandins, it’s important to emphasize the broad spectrum of activity, the fungicidal activity against the majority of Candida spp., and the activity against the biofilm. Furthermore, echinocandins show greater efficacy than conventional amphotericin B and fluconazole, and similar efficacy to liposomal amphotericin B (but they are less toxic). Finally, echinocandins are recommended at the highest level of evidence (AI) for the treatment of invasive candidiasis by IDSA and ESCMID guidelines.
Publisher SEEd
Date 2013-08-15
Type info:eu-repo/semantics/article

Format text/html
Source Reviews in Health Care; Vol 4, No 2S (2013); 5-12
Language eng

Rights Copyright (c) 2013 Seed

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