Tolerability and safety of antifungal drugs

Reviews in Health Care

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Field Value
Title Tolerability and safety of antifungal drugs
Creator Scaglione, Francesco
Subject Clinical Medicine
Antifungals; Tolerability; Safety
Description When treating critically ill patients, as those with fungal infections, attention should be focused on the appropriate use of drugs, especially in terms of dose, safety, and tolerability. The fungal infection itself and the concomitant physiological disorders concur to increase the risk of mortality in these patients, therefore the use of any antifungal agent should be carefully evaluated, considering both the direct action on the target fungus and the adverse effects eventually caused. Among antifungal drugs, echinocandins have the greatest tolerability. In fact, unlike amphotericin B, showing nephrotoxicity, and azoles, which are hepatotoxic, the use of echinocandins doesn’t result in major adverse events.
Publisher SEEd
Date 2013-08-15
Type info:eu-repo/semantics/article

Format text/html
Source Reviews in Health Care; Vol 4, No 2S (2013); 13-20
Language eng

Rights Copyright (c) 2013 Seed

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