Ledipasvir/sofosbuvir: the fixed dose combination in the new era of treatment for HCV

Reviews in Health Care

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Field Value
 
Title Ledipasvir/sofosbuvir: the fixed dose combination in the new era of treatment for HCV
 
Creator Ciancio, Alessia
 
Subject
Ledipasvir; Sofosbuvir; HCV
 
Description Interferon-based treatment is not suitable for many patients with hepatitis C virus (HCV) infection because of contraindications, other reasons for ineligibility and side-effects. The fixed dosed combination ledipasvir/sofosbuvir (LDV / SOF) is the first approved regimen that doesn’t require administration with interferon or ribavirin. LDV / SOF is also the first single-pill approved for the treatment of chronic HCV genotype 1 in both treatment-naïve and treatment-experienced patients. The results of the phase III studies demonstrate the combination has been very well tolerated and SVR rates consistently above 90%. Objective of this review is to present clinical evidence of efficacy and safety of the combination LDV / SOF in different subgroups of patients with HCV.
 
Publisher SEEd
 
Contributor
 
Date 2015-07-30
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion


 
Format text/html
application/pdf
 
Identifier https://journals.edizioniseed.it/index.php/rhc/article/view/1178
10.7175/rhc.v6i3.1178
 
Source Reviews in Health Care; Vol 6, No 3 (2015); 87-98
2038-6702
2038-6699
 
Language eng
 
Relation https://journals.edizioniseed.it/index.php/rhc/article/view/1178/1443
https://journals.edizioniseed.it/index.php/rhc/article/view/1178/1444
 
Coverage


 
Rights Copyright (c) 2015 Seed
http://creativecommons.org/licenses/by-nc/4.0
 

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