Red Blood Cell indices in patients with hypothyroidism
International Journal of Biomedical Research
View Publication Info| Field | Value | |
| Title |
Red Blood Cell indices in patients with hypothyroidism
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| Creator |
Jose, Antony
George, Peter |
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| Subject |
hypothyroidism
red blood cell indices hemoglobin thyroid function tests TFT PCV RBC count |
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| Description |
Background: Hypothyroidism is a common endocrine disorder in clinical practice. It is known to present with multiple systemic manifestations. As thyroid hormones play an important role in erythropoiesis; dysfunction usually result in hematological abnormalities. Aim and Objective: To study the RBC indices in hypothyroidism and to differentiate the pattern of anemia in patients on thyroid supplementation. Materials and methods: This cross-sectional observational study was done among 60 hypothyroid subjects attending to a tertiary care center at Mangalore. Thyroid Function Tests (TFT) and Red Blood Cell indices were obtained and analysed using SPSS software v20. Results: Among 60 hypothyroid subjects, 54 (90%) were females and 6 (10%) were males. The prevalence of anemia was 60% (n=36); among whom biochemically 14 were euthyroid and 22 had overt hypothyroid status. Among these subjects; 20 had normocytic, 12 had microcytic and 4 had macrocytic anemias. The mean haemoglobin in the study population was 11.91 ± 2.26 g/dl. Statistically significant lower levels of haemoglobin, PCV and RBC count where seen among overt hypothyroids as compared to euthyroids. Conclusion: Overt hypothyroid subjects had lower hemoglobin, PCV and RBC counts as compared to euthyroids. Early identification and treatment of hypothyroidism could prevent or revert the hematological changes; thus ensuring better quality of life. |
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| Publisher |
Scholar Science Journals
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| Date |
2020-09-30
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
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| Format |
application/pdf
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| Identifier |
https://ssjournals.com/index.php/ijbr/article/view/5494
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| Source |
International Journal of Biomedical Research; Vol. 11 No. 8 (2020): Aug; e5494
0976-9633 2455-0566 |
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| Language |
eng
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| Relation |
https://ssjournals.com/index.php/ijbr/article/view/5494/3698
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| Rights |
Copyright (c) 2020 International Journal of Biomedical Research
http://creativecommons.org/licenses/by/4.0 |
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