Red Blood Cell indices in patients with hypothyroidism

International Journal of Biomedical Research

View Publication Info
 
 
Field Value
 
Title Red Blood Cell indices in patients with hypothyroidism
 
Creator Jose, Antony
George, Peter
 
Subject hypothyroidism
red blood cell indices
hemoglobin
thyroid function tests
TFT
PCV
RBC count
 
Description Background: Hypothyroidism is a common endocrine disorder in clinical practice. It is known to present with multiple systemic manifestations. As thyroid hormones play an important role in erythropoiesis; dysfunction usually result in hematological abnormalities.
Aim and Objective: To study the RBC indices in hypothyroidism and to differentiate the pattern of anemia in patients on thyroid supplementation.
Materials and methods: This cross-sectional observational study was done among 60 hypothyroid subjects attending to a tertiary care center at Mangalore. Thyroid Function Tests (TFT) and Red Blood Cell indices were obtained and analysed using SPSS software v20.
Results: Among 60 hypothyroid subjects, 54 (90%) were females and 6 (10%) were males. The prevalence of anemia was 60% (n=36); among whom biochemically 14 were euthyroid and 22 had overt hypothyroid status. Among these subjects; 20 had normocytic, 12 had microcytic and 4 had macrocytic anemias. The mean haemoglobin in the study population was 11.91 ± 2.26 g/dl. Statistically significant lower levels of haemoglobin, PCV and RBC count where seen among overt hypothyroids as compared to euthyroids.
Conclusion: Overt hypothyroid subjects had lower hemoglobin, PCV and RBC counts as compared to euthyroids. Early identification and treatment of hypothyroidism could prevent or revert the hematological changes; thus ensuring better quality of life.
 
Publisher Scholar Science Journals
 
Date 2020-09-30
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://ssjournals.com/index.php/ijbr/article/view/5494
 
Source International Journal of Biomedical Research; Vol. 11 No. 8 (2020): Aug; e5494
0976-9633
2455-0566
 
Language eng
 
Relation https://ssjournals.com/index.php/ijbr/article/view/5494/3698
 
Rights Copyright (c) 2020 International Journal of Biomedical Research
http://creativecommons.org/licenses/by/4.0
 

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