Point of Admission Serum Electrolyte Profile of Children with Acute Diarrhoea in a Nigerian Tertiary Hospital

International Journal of Biomedical Research

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Field Value
 
Title Point of Admission Serum Electrolyte Profile of Children with Acute Diarrhoea in a Nigerian Tertiary Hospital
 
Creator Ugege, Modupe Omoshalewa
Chikani, Ugo Nnena
Ibitoye, Paul Kehinde
Yusuf, Tahir
Omar, Memunat
Adamu, Asmau
Ilah, Bilkisu Garba
 
Subject Hyponatraemia
hypokalaemia
metabolic acidosis
children
diarrhoea duration
 
Description Aim and Objective: This study aimed to describe the point-of-admission serum electrolyte profile of children with acute diarrhoea and to determine the associated factors.
Materials and Methods: The serum electrolyte at admission, bio data, clinical features and outcome of children aged 29 days to 15 years with primary diagnosis of acute diarrhoea, seen between January 1st, and December 31st, 2016 in the department of Paediatrics, UDUTH, Sokoto, were retrospectively analysed.
Results: Of the total of 154 subjects, 101(65.6%) were males giving a M: F ratio of 1.9: 1. Majority, 140(91.0%) were ? 36 months. Twenty four (15.6%), 105(68.2%), 14(9.1%) were mildly, moderately and severely dehydrated respectively while 11(7.1%) were not dehydrated. Hyponatraemia, hypokalaemia and metabolic acidosis occurred in 100(64.9%), 67(43.5%) and 21(13.6%) subjects, respectively. There were 10(6.5%) deaths. Only potassium level was significantly affected by degree of dehydration (p = 0.02). Duration of diarrhoea greater or equal to 3 days and greater or equal to 7 days before presentation was significantly associated with metabolic acidosis and hypokalaemia (p= 0.03 and 0.001) respectively. Diarrhoea duration more than 3 days and under nutrition were associated with death.
Conclusion: The degree of dehydration appears to be a good predictor of the occurrence of hypokalaemia. Diarrhoea duration is a risk factor for metabolic acidosis, hypokalaemia and death. We recommend intensified community health education on appropriate home treatment and prompt hospital presentation once diarrhoea duration is more than three days, to prevent deleterious diarrhoea consequences.
 
Publisher Scholar Science Journals
 
Date 2020-02-29
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://ssjournals.com/index.php/ijbr/article/view/5315
10.7439/ijbr.v11i02.5315
 
Source International Journal of Biomedical Research; Vol. 11 No. 02 (2020): Feb; e5315
0976-9633
2455-0566
 
Language eng
 
Relation https://ssjournals.com/index.php/ijbr/article/view/5315/3628
 
Rights Copyright (c) 2020 International Journal of Biomedical Research
 

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