Relationship between clinical findings and spirometry parameters among patients with mild asthma

American Journal of Experimental and Clinical Research

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Field Value
 
Title Relationship between clinical findings and spirometry parameters among patients with mild asthma
 
Creator saburi, amin
ghanei, mostafa
hajihashemi, ali
 
Subject Internal Medicine
Relationship, mild Asthma, Spirometry, clinical findings.
asthma, internal medicine
 
Description Few studies have been done regarding the concordance of association of clinical findings and spirometric parameters especially in patients with mild asthma. In this study we evaluated the relationship between clinical findings and spirometric parameters among patients with mild asthma. In an analytical cross-sectional study, we evaluated patients who were referred to the Baqiyatallah university hospital during the year 2009 because of mild asthma symptoms. Before beginning the treatment, patients were examined by a pulmonologist and all of them underwent spirometric evaluation. A total of 68 patients were enrolled in the study. The mean age was 43.78±10.74 years and 52.9% of cases were male). Regarding the bivariate analysis, there was a significant correlation between clinical findings and spirometric parameters. In multivariate analysis, a significant correlation was found between FVC values and wheezing (P=0.007, β=-0.351), FVC values and coughing (P=0.028, β=+0.272), FEV1 values and wheezing (P<0.001, β=-0.440) and FEV1 values and dyspnea (P=0.014, β=+0.276), also FEV1/FVC values and a family history of asthma (P=0.001, β=+0.370), FEV1/FVC values and wheezing (P=0.001, β=-0.365), FEV1/FEV values and dyspnea (P=0.009, β=-0.283) and finally for the wheezing and MEF values (P<0.001, β=-0.615). In conclusion, although in the previous studies the exact relationship between any of the spirometric indices and clinical symptoms has not been described, it seems that wheezing rather than the other clinical findings may be correlated with spirometric indices, however further studies with larger sample size are necessary.
 
Publisher American Journal of Experimental & Clinical Research
 
Contributor
 
Date 2015-07-14
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
cross sectional
 
Format application/pdf
 
Identifier http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/45
 
Source American Journal of Experimental and Clinical Research; Vol 2, No 3 (2015); 113-117
2330-9245
2330-9237
 
Language eng
 
Relation http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/45/124
 
Rights Authors who publish with the American Journal of Experimental and Clinical Resaerch (AJECR) agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-NC-ND) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
 

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