Prevalence of benign tumors among patients with multiple sclerosis

American Journal of Experimental and Clinical Research

View Publication Info
 
 
Field Value
 
Title Prevalence of benign tumors among patients with multiple sclerosis
 
Creator Rafiee Zadeh, Aryan; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences and Multiple Sclerosis and Neuroimmunology Research Center, Isfahan, Iran
Farrokhi, Mehrdad; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences and Multiple Sclerosis and Neuroimmunology Research Center, Isfahan, Iran
Etemadifar, Masoud; Department of Neurology, School of Medicine, Isfahan University of Medical Sciences and Multiple Sclerosis and Neuroimmunology Research Center, Isfahan, Iran
Amani Beni, Ali; Department of Biology, Faculty of Sciences, University of Isfahan, Isfahan, Iran Nour Danesh Institute of Higher Education, Meymeh, Isfahan, Iran
 
Subject Medicine
Multiple sclerosis, benign tumors, pituitary adenoma, meningioma, lipoma

 
Description Multiple sclerosis (MS), an inflammatory autoimmune disease, affects almost 1% of world’s population in which myelin sheaths of neurons are targeted by immune cells. Association of different factors and diseases with MS provides new insights into possible pathogenesis and treatment for this disease. In this regard, we investigated the association of benign tumors with MS disease by studying total Isfehan multiple sclerosis (TIMS) records for MS patients registered in Isfahan Multiple Sclerosis Society (IMSS) who had developed any kind of benign tumors whether before MS diagnosis or after it. This study was performed in Isfahan province, third large province of Iran, with 4,815,863 populations located 1590 meters above sea level between latitudes 30 and 34 degrees north of the equator, and longitude 49-55 east. Among 4950 registered patients, 28 patients were discovered to have three types of benign tumors; pituitary adenoma in 22, meningioma in 5 and lipoma in 1 patient. The incidence rate of developing pituitary adenoma and meningioma were higher than in general population (OR 95%CI: 1.110; range: 0.731-1.685 and 1.035; range: 0.431-2.487 respectively) but these findings were not statistically significant (p= 0.624 for pituitary adenoma and p= 0.939 for meningioma). But the incidence rate for lipoma was lower among MS patients (OR 95%CI: 0.020; range: 0.003-0.143) which was statistically significant (p <0.001).
 
Publisher American Journal of Experimental & Clinical Research
 
Contributor
 
Date 2015-10-12
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article

 
Format application/pdf
 
Identifier http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/55
 
Source American Journal of Experimental and Clinical Research; Vol 2, No 4 (2015); 127-132
2330-9245
2330-9237
 
Language eng
 
Relation http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/55/139
 
Rights Authors who publish with the American Journal of Experimental and Clinical Resaerch (AJECR) agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (CC BY-NC-ND) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2016 Simon Fraser University Library