Erythropoietin (EPO)

Medicina y Laboratorio

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Title Erythropoietin (EPO)
Eritropoyetina (EPO)
Creator de los Ríos-Morales, Luz Adriana
Guevara-Arismendy, Natalia M.
Vizcaíno-Carruyo, Jennifer C.
Toro-Montoya, Ana Isabel
Description Erythropoietin (EPO) is a glycoprotein hormone produced mainly in the peritubular cells of the kidneys, which regulates erythrocyte production and differentiation. Erythropoietin synthesis is regulated by changes in oxygen availability, that is, the higher the oxygen, the lower the EPO production, and vice versa. EPO binds to receptors on CD34 + hematopoietic stem cells, promoting the activation of genes to stimulate their proliferation and differentiation into mature erythrocytes
La eritropoyetina (EPO) es una hormona glucoproteica producida principalmente en las células peritubulares de los riñones, que regula la producción y diferenciación eritrocitaria. La síntesis de eritropoyetina está regulada por cambios en la disponibilidad del oxígeno, es decir, a mayor cantidad de oxígeno, menor producción de EPO, y a la inversa. La EPO se une a los receptores en las células madre hematopoyéticas CD34+, promoviendo la activación de los genes para estimular su proliferación y diferenciación hasta eritrocitos maduros.
Publisher EDIMECO S.A.
Date 2020-09-29
Type info:eu-repo/semantics/article
Format application/pdf
Source Medicina & Laboratorio; Vol. 24 No. 4 (2020): Octubre-Diciembre; 344-347
Medicina y Laboratorio; Vol. 24 Núm. 4 (2020): Octubre-Diciembre; 344-347
Language spa
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