Hybrid micro-/nanogels for optical sensing and intracellular imaging

Nano Reviews & Experiments

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Field Value
 
Title Hybrid micro-/nanogels for optical sensing and intracellular imaging
 
Creator Wu, Weitai
Zhou, Shuiqin
 
Subject
 
Description Hybrid micro-/nanogels are playing an increasing important part in a diverse range of applications, due to their tunable dimensions, large surface area, stable interior network structure, and a very short response time. We review recent advances and challenges in the developments of hybrid micro-/nanogels toward applications for optical sensing of pH, temperature, glucose, ions, and other species as well as for intracellular imaging. Due to their unique advantages, hybrid micro-/nanogels as optical probes are attracting substantial interests for continuous monitoring of chemical parameters in complex samples such as blood and bioreactor fluids, in chemical research and industry, and in food quality control. In particular, their intracellular probing ability enables the monitoring of the biochemistry and biophysics of live cells over time and space, thus contributing to the explanation of intricate biological processes and the development of novel diagnoses. Unlike most other probes, hybrid micro-/nanogels could also combine other multiple functions into a single probe. The rational design of hybrid micro-/ nanogels will not only improve the probing applications as desirable, but also implement their applications in new arenas. With ongoing rapid advances in bionanotechnology, the well-designed hybrid micro-/nanogel probes will be able to provide simultaneous sensing, imaging diagnosis, and therapy toward clinical applications. Keywords: stimuli-responsive polymer; microgel; nanogel; hybrids; optical biosensor; cell imaging; intracellular detection (Published: 9 December 2010) Citation: Nano Reviews 2010, 1: 5730 - DOI: 10.3402/nano.v1i0.5730
 
Publisher Co-Action Publishing
 
Contributor
 
Date 2010-12-09
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
text/html
text/xml
 
Identifier http://www.nanoreviewsexperiments.net/index.php/nano/article/view/5730
10.3402/nr.v1i0.5730
 
Source Nano Reviews & Experiments; Vol 1 (2010) incl Supplements
2002-2727
 
Language eng
 
Relation http://www.nanoreviewsexperiments.net/index.php/nano/article/view/5730/6478
http://www.nanoreviewsexperiments.net/index.php/nano/article/view/5730/6480
http://www.nanoreviewsexperiments.net/index.php/nano/article/view/5730/6479
 

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