Impact of albumin levels on clinical outcomes in children underwent abdominal surgery

Paediatrica Indonesiana

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Field Value
 
Title Impact of albumin levels on clinical outcomes in children underwent abdominal surgery
 
Creator Dewi, Rismala
Silitonga, Freddy Guntur Mangapul
Mangunatmadja, Irawan
 
Description Background Patients underwent abdominal surgery and had hypoalbuminemia were at risk of post-operative complications. The prognostic role of albumin levels in children with abdominal surgery remains unclear.
Objective To investigate the impact of albumin levels on clinical outcomes related to the complications in children with abdominal surgery.
Methods This was a retrospective cohort study on children aged 29 days to 18 years, who underwent abdominal surgery, had serum albumin levels measured at pre-operative and within 48 hours post-operatively, and hospitalized in Paediatric Intensive Care Unit of Dr. Cipto Mangunkusumo Hospital, Indonesia. The primary outcomes were post-operative complications (sepsis, surgical site infection, shock), length of stay in PICU, dehiscence, relaparotomy, and postoperative mortality.
Results This study recruited a total of 201 children. Pre- and post-operative serum albumin levels of ≤ 3.00 g/dL were found in 15.4% and 51.2%, respectively. Pre- and post-operative serum albumin levels of ≤ 3.00 g/dL were associated with higher risk of post-operative sepsis (RR 3.4; 95%CI 1.54 to 7.51) and relaparotomy (RR 3.84; 95%CI 1.28 to 1.49). The median of length of PICU stay was 4 days longer in children with pre-operative serum albumin levels ≤ 3.00 g/dL (P<0.001).
Conclusions Hypoalbuminemia condition in children undergo abdominal surgery is associated with increased risk of post-operative sepsis, longer length of stay in PICU, and risk of relaparotomy.
 
Publisher Indonesian Pediatric Society
 
Date 2020-06-12
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2377
 
Source Paediatrica Indonesiana; Vol 60 No 3 (2020): May 2020
2338-476X
0030-9311
10.14238/pi60.3.2020
 
Language eng
 
Relation https://paediatricaindonesiana.org/index.php/paediatrica-indonesiana/article/view/2377/2023
 
Rights Copyright (c) 2020 Rismala Dewi, Freddy Guntur Mangapul Silitonga, Irawan Irawan Mangunatmadja
http://creativecommons.org/licenses/by-nc-sa/4.0
 

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