HAMBATAN MESENCHYMAL STEM CELL TERHADAP PROLIFERASI LIMFOSIT T

Majalah Biomorfologi

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Field Value
 
Title HAMBATAN MESENCHYMAL STEM CELL TERHADAP PROLIFERASI LIMFOSIT T
 
Creator Fajarwati, Sofia
 
Subject Mesenchymal stem cells; T cell proliferation; immunosuppresion; proliferasi sel T; imunosupresi
 
Description Mesenchymal stem cells(MSCs) are a kind of stem cells that can differentiate into several kinds of mesodermal cell decent. MSCs can be cultured in vitro therefore it can serve many purposes. However, MSCs also have immunosuppresion effects, one of the way is by suppresing T cell proliferation. MSCs need cell-to-cell contact with activated T cells in certain rasio to release it’s surppresion properties. Primery help from inflamatory cytokines is also needed. MSCs’s suppresion effect can be mediated by several molecules such asindoleamine 2,3-dioxygenase (IDO), inducible nitric-oxide synthase (iNOS), prostaglandin E2 (PGE2), transform growth factor-β (TGF-β), hepatocyte growth factor (HGF), and HLA-G5 soluble. MSCs’s characteristic and culture conditions can affect clinical applications.
 
Publisher Department of Anatomy and Histology, Faculty of Medicine, Universitas Airlangga
 
Contributor
 
Date 2019-11-15
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://e-journal.unair.ac.id/MBIO/article/view/15995
10.20473/mbiom.v27i2.2014.24-29
 
Source Majalah Biomorfologi; Vol 27, No 2 (2014): Majalah Biomorfologi; 24-29
2716-0920
0215-8833
 
Language eng
 
Relation https://e-journal.unair.ac.id/MBIO/article/view/15995/8624
 
Rights Copyright (c) 2019 Majalah Biomorfologi
http://creativecommons.org/licenses/by-nc-sa/4.0
 

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