Hepatitis B Screening Prior to Chemotherapy in the Middle East: A Retrospective Cohort Study
The International Arabic Journal of Antimicrobial Agents
View Publication Info| Field | Value | |
| Title |
Hepatitis B Screening Prior to Chemotherapy in the Middle East: A Retrospective Cohort Study
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| Creator |
Ziade, Nathalie
Hosni, Mohammad Barada, Kassem Bizri, Abdul Rahman |
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| Description |
Background: Hepatitis B virus (HBV) reactivation can be asymptomatic or manifest as fatal fulminant hepatitis. Most international guidelines recommend screening patients prior to immunosuppressive therapy. Aims: To determine HBV screening rates and modalities in patients receiving chemotherapy at the American University of Beirut Medical Center. Methods: A retrospective cohort review of electronic health records of adult patients who received chemotherapeutic agents, between June 2015 and June 2016. Patients clinical characteristics were documented. Adequate screening was defined as performing all: HBsAg, HBs Abs, and anti HBc Abs(total). Results: A total of 1547 patients were initially assessed. 45.6% were males with a mean age of 56. 382(30%) had hematologic malignancies, of whom 111 underwent HSCT. Of those included, 303(24%) patients were screened by at least one test for HBV and 42(3.3%) for HBsAg, anti HBc Abs and HBs Abs. Patients who were appropriately screened were significantly younger(p=0.008) and more likely to have hematologic malignancies (n=35, 83.3%, p<0.0001). Among patients with hematologic malignancies, appropriately screened patients (n=35) were younger (p=0.042) and had a history of HSCT(n=19, 54.3%, p=0.001). Conclusion: Rates of screening for HBV prior to chemotherapy at our medical center are low, and not always complete or adequate. There is an urgent need to implement a better screening policy. |
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| Publisher |
International Medical Publisher
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| Date |
2020-05-07
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| Type |
info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion Peer-reviewed Article |
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| Format |
application/pdf
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| Identifier |
http://imed.pub/ojs/index.php/IAJAA/article/view/2363
10.3823/842 |
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| Source |
The International Arabic Journal of Antimicrobial Agents; Vol 10 No 1 (2020)
2174-9094 |
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| Language |
eng
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| Relation |
http://imed.pub/ojs/index.php/IAJAA/article/view/2363/2098
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| Rights |
Copyright (c) 2020 Nathalie Ziade, Mohammad Hosni, Kassem Barada, Abdul Rahman Bizri
http://creativecommons.org/licenses/by/4.0 |
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