Urine culture: an unavoidable test for specific diagnosis of urinary tract infection and rational use of antibiotics

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Title Urine culture: an unavoidable test for specific diagnosis of urinary tract infection and rational use of antibiotics
El urocultivo: prueba ineludible para el diagnóstico específico de la infección del tracto urinario y el uso racional de los antibióticos
 
Creator López Vargas, Jaime Alberto
Campuzano Maya, Germán
 
Subject Urinary tract infections; urine specimen collection; anti-bacterial agents; drug resistance, bacterial.
infecciones urinarias, toma de muestras de orina, antibacterianos, farmacorresistencia bacteriana.
 
Description Urinary tract infections are the third most common infection among humans and the second reason why antibiotics are prescribed. Urine cultures are the culture most commonly requested to microbiology laboratories and this test remains as the gold standard for diagnosis. This review article includes aspects such as aetiology of the infection and issues related with empiric antimicrobials use to treat community acquired urinary tract infections. In addition, basic laboratory tests that support diagnosis of urinary tract infections are analyzed; it is also described aspects related with urine culture, since when this study is indicated until the final report and interpretation of results, in order to promote rational use of antibiotics. Thus, besides of help to reduce collateral effects of antibiotic use, it also improves cost-benefit of diagnosis-treatment process, and the most important, to recover patient’s health.
Las infecciones del tracto urinario son la tercera infección más frecuente que se presenta en el ser humano y la segunda razón por la cual se prescriben antibióticos. Los cultivos de las muestras de orina (urocultivos) son el cultivo más solicitado a los laboratorios de microbiología y continúan siendo la prueba de referencia para su diagnóstico. En este artículo de revisión se tratan aspectos como la etiología y la problemática de la resistencia a los principales antibióticos que se emplean de manera empírica para el tratamiento de las infecciones del tracto urinario adquiridas en la comunidad. Además, se analizan las pruebas de laboratorio básicas que apoyan el diagnóstico de esta infección; se detallan los aspectos relacionados con el urocultivo, desde el cuándo está indicado solicitarlo hasta el informe final y la interpretación de los resultados, con el fin de promover un uso racional de los antibióticos. De esta manera, además de contribuir a disminuir el efecto colateral del empleo de antibióticos, se mejora el costo-beneficio del proceso diagnóstico-tratamiento y lo fundamental, se recupera la salud del paciente.
 
Publisher EDIMECO S.A.
 
Date 2013-05-01
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://medicinaylaboratorio.com/index.php/myl/article/view/226
 
Source Medicina & Laboratorio; Vol. 19 No. 5-6 (2013); 211-242
Medicina y Laboratorio; Vol. 19 Núm. 5-6 (2013); 211-242
2500-7106
0123-2576
 
Language spa
 
Relation https://medicinaylaboratorio.com/index.php/myl/article/view/226/212
/*ref*/Najar MS, Saldanha CL, Banday KA. Approach to urinary tract infections. Indian J Nephrol 2009;19:129-139. https://doi.org/10.4103/0971-4065.59333
/*ref*/Wagenlehner FM, Hoyme U, Kaase M, Funfstuck R, Naber KG, Schmiemann G. Uncomplicated urinary tract infections. Dtsch Arztebl Int 2011;108:415-423. https://doi.org/10.3238/arztebl.2011.0415
/*ref*/Dielubanza EJ, Schaeffer AJ. Urinary tract infections in women. Med Clin North Am 2011;95:27-41. https://doi.org/10.1016/j.mcna.2010.08.023
/*ref*/Prieto J, García-Rodríguez JA, Barberán J, Granizo JJ, Rodicio MP, González J. Un día en la Microbiología española. Estudio descriptivo de la actividad de los Servicios de Microbiología Clínica. Rev Esp Quimioter 2008;21|:206-212.
/*ref*/Wilson ML, Gaido L. Laboratory diagnosis of urinary tract infections in adult patients. Clin Infect Dis 2004;38:1150-1158. https://doi.org/10.1086/383029
/*ref*/Foxman B. Epidemiology of urinary tract infections: incidence, morbidity, and economic costs. Am J Med 2002;113 Suppl 1A:5S-13S. https://doi.org/10.1016/S0002-9343(02)01054-9
/*ref*/McCarter YS, Burd EM, Hall GS, Zervos M, Sharp SE. Cumitech 2C: Laboratory Diagnosis of Urinary Tract Infections. Washington, DC: ASM Press, 2009.
/*ref*/Fihn SD. Clinical practice. Acute uncomplicated urinary tract infection in women. N Engl J Med 2003;349:259-266. https://doi.org/10.1056/NEJMcp030027
/*ref*/Gupta K, Hooton TM, Naber KG, Wullt B, Colgan R, Miller LG, et al. International clinical practice guidelines for the treatment of acute uncomplicated cystitis and pyelonephritis in women: A 2010 update by the Infectious Diseases Society of America and the European Society for Microbiology and Infectious Diseases. Clin Infect Dis 2011;52:e103-120. https://doi.org/10.1093/cid/ciq257
/*ref*/Miller LG, Tang AW. Treatment of uncomplicated urinary tract infections in an era of increasing antimicrobial resistance. Mayo Clin Proc 2004;79:1048-1053; quiz 1053-1044. https://doi.org/10.4065/79.8.1048
/*ref*/Montini G, Tullus K, Hewitt I. Febrile urinary tract infections in children. N Engl J Med 2011;365:239-250. https://doi.org/10.1056/NEJMra1007755
/*ref*/Zorc JJ, Kiddoo DA, Shaw KN. Diagnosis and management of pediatric urinary tract infections. Clin Microbiol Rev 2005;18:417-422. https://doi.org/10.1128/CMR.18.2.417-422.2005
/*ref*/Saadeh SA, Mattoo TK. Managing urinary tract infections. Pediatr Nephrol 2011;26:1967-1976. https://doi.org/10.1007/s00467-011-1801-5
/*ref*/Klevens RM, Edwards JR, Richards CL, Jr., Horan TC, Gaynes RP, Pollock DA, et al. Estimating health care-associated infections and deaths in U.S. hospitals, 2002. Public Health Rep 2007;122:160-166. https://doi.org/10.1177/003335490712200205
/*ref*/Nicolle LE, Bradley S, Colgan R, Rice JC, Schaeffer A, Hooton TM. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005;40:643-654. https://doi.org/10.1086/427507
/*ref*/Knottnerus BJ, Bindels PJ, Geerlings SE, Moll van Charante EP, ter Riet G. Optimizing the diagnostic work-up of acute uncomplicated urinary tract infections. BMC Fam Pract 2008;9:64. https://doi.org/10.1186/1471-2296-9-64
/*ref*/Rubin RH, Shapiro ED, Andriole VT, Davis RJ, Stamm WE. Evaluation of new anti-infective drugs for the treatment of urinary tract infection. Infectious Diseases Society of America and the Food and Drug Administration. Clin Infect Dis 1992;15 Suppl 1:S216-227. https://doi.org/10.1093/clind/15.Supplement_1.S216
/*ref*/Schmiemann G, Kniehl E, Gebhardt K, Matejczyk MM, Hummers-Pradier E. The diagnosis of urinary tract infection: a systematic review. Dtsch Arztebl Int 2010;107:361-367. https://doi.org/10.3238/arztebl.2010.0361
/*ref*/Nicolle LE. Complicated urinary tract infection in adults. Can J Infect Dis Med Microbiol 2005;16:349-360. https://doi.org/10.1155/2005/385768
/*ref*/Hummers-Pradier E, Kochen MM. Urinary tract infections in adult general practice patients. Br J Gen Pract 2002;52:752-761.
/*ref*/Hooton TM, Bradley SF, Cardenas DD, Colgan R, Geerlings SE, Rice JC, et al. Diagnosis, prevention, and treatment of catheter-associated urinary tract infection in adults: 2009 International Clinical Practice Guidelines from the Infectious Diseases Society of America. Clin Infect Dis 2010;50:625-663. https://doi.org/10.1086/650482
/*ref*/Kodner CM, Thomas Gupton EK. Recurrent urinary tract infections in women: diagnosis and management. Am Fam Physician 2010;82:638-643.
/*ref*/Mathai D, Jones RN, Pfaller MA. Epidemiology and frequency of resistance among pathogens causing urinary tract infections in 1,510 hospitalized patients: a report from the SENTRY Antimicrobial Surveillance Program (North America). Diagn Microbiol Infect Dis 2001;40:129-136. https://doi.org/10.1016/S0732-8893(01)00254-1
/*ref*/Bahadin J, Teo SS, Mathew S. Aetiology of community-acquired urinary tract infection and antimicrobial susceptibility patterns of uropathogens isolated. Singapore Med J 2011;52:415-420.
/*ref*/Grude N, Tveten Y, Jenkins A, Kristiansen BE. Uncomplicated urinary tract infections. Bacterial findings and efficacy of empirical antibacterial treatment. Scand J Prim Health Care 2005;23:115-119. https://doi.org/10.1080/02813430510015287
/*ref*/Linhares I, Raposo T, Rodrigues A, Almeida A. Frequency and antimicrobial resistance patterns of bacteria implicated in community urinary tract infections: a ten-year surveillance study (2000-2009). BMC Infect Dis 2013;13:19. https://doi.org/10.1186/1471-2334-13-19
/*ref*/Akoachere JF, Yvonne S, Akum NH, Seraphine EN. Etiologic profile and antimicrobial susceptibility of community-acquired urinary tract infection in two Cameroonian towns. BMC Res Notes 2012;5:219. https://doi.org/10.1186/1756-0500-5-219
/*ref*/Jones RN, Kugler KC, Pfaller MA, Winokur PL. Characteristics of pathogens causing urinary tract infections in hospitals in North America: results from the SENTRY Antimicrobial Surveillance Program, 1997. Diagn Microbiol Infect Dis 1999;35:55-63. https://doi.org/10.1016/S0732-8893(98)00158-8
/*ref*/Hidron AI, Edwards JR, Patel J, Horan TC, Sievert DM, Pollock DA, et al. NHSN annual update: antimicrobial-resistant pathogens associated with healthcare-associated infections: annual summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2006-2007. Infect Control Hosp Epidemiol 2008;29:996-1011. https://doi.org/10.1086/591861
/*ref*/Bouza E, San Juan R, Munoz P, Voss A, Kluytmans J. A European perspective on nosocomial urinary tract infections I. Report on the microbiology workload, etiology and antimicrobial susceptibility (ESGNI-003 study). European Study Group on Nosocomial Infections. Clin Microbiol Infect 2001;7:523-531. https://doi.org/10.1046/j.1198-743x.2001.00326.x
/*ref*/Wagenlehner FM, Niemetz AH, Weidner W, Naber KG. Spectrum and antibiotic resistance of uropathogens from hospitalised patients with urinary tract infections: 1994-2005. Int J Antimicrob Agents 2008;31 Suppl 1:S25-34. https://doi.org/10.1016/j.ijantimicag.2007.07.029
/*ref*/Kim ME, Ha US, Cho YH. Prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in female outpatients in South Korea: a multicentre study in 2006. Int J Antimicrob Agents 2008;31 Suppl 1:S15-18. https://doi.org/10.1016/j.ijantimicag.2007.07.043
/*ref*/Achkar JM, Fries BC. Candida infections of the genitourinary tract. Clin Microbiol Rev 2010;23:253-273. https://doi.org/10.1128/CMR.00076-09
/*ref*/Weber G, Riesenberg K, Schlaeffer F, Peled N, Borer A, Yagupsky P. Changing trends in frequency and antimicrobial resistance of urinary pathogens in outpatient clinics and a hospital in Southern Israel, 1991-1995. Eur J Clin Microbiol Infect Dis 1997;16:834-838. https://doi.org/10.1007/BF01700414
/*ref*/Gupta K, Sahm DF, Mayfield D, Stamm WE. Antimicrobial resistance among uropathogens that cause community-acquired urinary tract infections in women: a nationwide analysis. Clin Infect Dis 2001;33:89-94. https://doi.org/10.1086/320880
/*ref*/Castro-Orozco R, Barreto-Maya AC, Guzmán-Álvarez H, Ortega-Quiroz RJ, Benítez-Peña L. Patrones de resistencia antimicrobiana en uropatógenos gramnegativos aislados de pacientes ambulatorios y hospitalizados Cartagena, 2005-2008. Rev Salud Pública 2010;12:1010-1019. https://doi.org/10.1590/S0124-00642010000600013
/*ref*/Álvarez-Barranco LC. Infecciones de vías urinarias en el Hospital Universidad del Norte. Salud Uninorte 2007;23:9-18.
/*ref*/Gómez CP, Plata M, Sejnaui J, Rico CL, Vanegas S. Resistencia de la E.coli en urocultivos de pacientes con sospecha de infección urinaria intra y extra-hospitalaria en la Fundación Santa Fe de Bogotá. Urol Colomb 2009;18:53-58.
/*ref*/Grupo GERMEN (Grupo de Estudio de Resistencia de Medellín). http://www.grupogermen.org/pdf/escherichia.pdf Consultado en marzo de 2013.
/*ref*/Carlet J, Jarlier V, Harbarth S, Voss A, Goossens H, Pittet D. Ready for a world without antibiotics? The Pensieres Antibiotic Resistance Call to Action. Antimicrob Resist Infect Control 2012;1:11. https://doi.org/10.1186/2047-2994-1-11
/*ref*/Sader HS, Jones RN, Winokur PL, Pfaller MA, Doern GV, Barrett T. Antimicrobial susceptibility of bacteria causing urinary tract infections in Latin American hospitals: results from the SENTRY Antimicrobial Surveillance Program (1997). Clin Microbiol Infect 1999;5:478-487. https://doi.org/10.1111/j.1469-0691.1999.tb00177.x
/*ref*/Gales AC, Sader HS, Jones RN. Urinary tract infection trends in Latin American hospitals: report from the SENTRY antimicrobial surveillance program (1997-2000). Diagn Microbiol Infect Dis 2002;44:289-299. https://doi.org/10.1016/S0732-8893(02)00470-4
/*ref*/Gordon KA, Jones RN. Susceptibility patterns of orally administered antimicrobials among urinary tract infection pathogens from hospitalized patients in North America: comparison report to Europe and Latin America. Results from the SENTRY Antimicrobial Surveillance Program (2000). Diagn Microbiol Infect Dis 2003;45:295-301. https://doi.org/10.1016/S0732-8893(02)00467-4
/*ref*/Sahm DF, Thornsberry C, Mayfield DC, Jones ME, Karlowsky JA. Multidrug-resistant urinary tract isolates of Escherichia coli: prevalence and patient demographics in the United States in 2000. Antimicrob. Agents Chemother 2001 https://doi.org/10.1128/AAC.45.5.1402-1406.2001
/*ref*/45: 1402-1406.]. . Antimicrob Agents Chemoter 2001;45:1402-1406. https://doi.org/10.1128/AAC.45.5.1402-1406.2001
/*ref*/Martinez P, Garzon D, Mattar S. CTX-M-producing Escherichia coli and Klebsiella pneumoniae isolated from community-acquired urinary tract infections in Valledupar, Colombia. Braz J Infect Dis 2012;16:420-425. https://doi.org/10.1016/j.bjid.2012.05.001
/*ref*/Kahlmeter G. The ECO*SENS Project: a prospective, multinational, multicentre epidemiological survey of the prevalence and antimicrobial susceptibility of urinary tract pathogens-interim report. J Antimicrob Chemother 2000;46 Suppl A:15-22. https://doi.org/10.1093/jac/46.suppl_1.15
/*ref*/De Backer D, Christiaens T, Heytens S, De Sutter A, Stobberingh EE, Verschraegen G. Evolution of bacterial susceptibility pattern of Escherichia coli in uncomplicated urinary tract infections in a country with high antibiotic consumption: a comparison of two surveys with a 10 year interval. J Antimicrob Chemother 2008;62:364-368. https://doi.org/10.1093/jac/dkn197
/*ref*/McIsaac WJ, Mazzulli T, Permaul J, Moineddin R, Low DE. Community-acquired antibiotic resistance in urinary isolates from adult women in Canada. Can J Infect Dis Med Microbiol 2006;17:337-340. https://doi.org/10.1155/2006/791313
/*ref*/Gupta K, Hooton TM, Wobbe CL, Stamm WE. The prevalence of antimicrobial resistance among uropathogens causing acute uncomplicated cystitis in young women. Int J Antimicrob Agents 1999;11:305-308. https://doi.org/10.1016/S0924-8579(99)00035-7
/*ref*/Kahlmeter G. An international survey of the antimicrobial susceptibility of pathogens from uncomplicated urinary tract infections: the ECO.SENS Project. J Antimicrob Chemother 2003;51:69-76. https://doi.org/10.1093/jac/dkg028
/*ref*/Muvunyi CM, Masaisa F, Bayingana C, Mutesa L, Musemakweri A, Muhirwa G, et al. Decreased susceptibility to commonly used antimicrobial agents in bacterial pathogens isolated from urinary tract infections in Rwanda: need for new antimicrobial guidelines. Am J Trop Med Hyg 2011;84:923-928. https://doi.org/10.4269/ajtmh.2011.11-0057
/*ref*/Akram M, Shahid M, Khan AU. Etiology and antibiotic resistance patterns of community-acquired urinary tract infections in J N M C Hospital Aligarh, India. Ann Clin Microbiol Antimicrob 2007;6:4. https://doi.org/10.1186/1476-0711-6-4
/*ref*/Andrade SS, Sader HS, Jones RN, Pereira AS, Pignatari AC, Gales AC. Increased resistance to first-line agents among bacterial pathogens isolated from urinary tract infections in Latin America: time for local guidelines? Mem Inst Oswaldo Cruz 2006;101:741-748. https://doi.org/10.1590/S0074-02762006000700006
/*ref*/Bours PH, Polak R, Hoepelman AI, Delgado E, Jarquin A, Matute AJ. Increasing resistance in community-acquired urinary tract infections in Latin America, five years after the implementation of national therapeutic guidelines. Int J Infect Dis 2010;14:e770-774. https://doi.org/10.1016/j.ijid.2010.02.2264
/*ref*/Hooton TM. Clinical practice. Uncomplicated urinary tract infection. N Engl J Med 2012;366:1028-1037. https://doi.org/10.1056/NEJMcp1104429
/*ref*/Bent S, Nallamothu BK, Simel DL, Fihn SD, Saint S. Does this woman have an acute uncomplicated urinary tract infection? JAMA 2002;287:2701-2710. https://doi.org/10.1001/jama.287.20.2701
/*ref*/Giesen LG, Cousins G, Dimitrov BD, van de Laar FA, Fahey T. Predicting acute uncomplicated urinary tract infection in women: a systematic review of the diagnostic accuracy of symptoms and signs. BMC Fam Pract 2010;11:78. https://doi.org/10.1186/1471-2296-11-78
/*ref*/Medina-Bombardo D, Jover-Palmer A. Does clinical examination aid in the diagnosis of urinary tract infections in women? A systematic review and meta-analysis. BMC Fam Pract 2011;12:111. https://doi.org/10.1186/1471-2296-12-111
/*ref*/Barry HC, Ebell MH, Hickner J. Evaluation of suspected urinary tract infection in ambulatory women: a cost-utility analysis of office-based strategies. J Fam Pract 1997;44:49-60.
/*ref*/Fenwick EA, Briggs AH, Hawke CI. Management of urinary tract infection in general practice: a cost-effectiveness analysis. Br J Gen Pract 2000;50:635-639.
/*ref*/Mishra B, Srivastava S, Singh K, Pandey A, Agarwal J. Symptom-based diagnosis of urinary tract infection in women: are we over-prescribing antibiotics? Int J Clin Pract 2012;66:493-498. https://doi.org/10.1111/j.1742-1241.2012.02906.x
/*ref*/McIsaac WJ, Low DE, Biringer A, Pimlott N, Evans M, Glazier R. The impact of empirical management of acute cystitis on unnecessary antibiotic use. Arch Intern Med 2002;162:600-605. https://doi.org/10.1001/archinte.162.5.600
/*ref*/Magee JT, Pritchard EL, Fitzgerald KA, Dunstan FD, Howard AJ. Antibiotic prescribing and antibiotic resistance in community practice: retrospective study, 1996-8. BMJ 1999;319:1239-1240. https://doi.org/10.1136/bmj.319.7219.1239
/*ref*/Campuzano-Maya G, Arbeláez-Gómez M. Uroanálisis: más que un examen de rutina. Medicina & Laboratorio 2006;12:511-556.
/*ref*/Ajayi AB, Nwabuisi C, Aboyeji PO, Fowotade A, Fakeye OO. Reliability of urine multistix and gram stain in the detection of asymptomatic bacteriuria in pregnancy. West Afr J Med 2010;29:339-343.
/*ref*/Awonuga DO, Fawole AO, Dada-Adegbola HO, Olola FA, Awonuga OM. Asymptomatic bacteriuria in pregnancy: evaluation of reagent strips in comparison to microbiological culture. Afr J Med Med Sci 2011;40:377-383.
/*ref*/Mignini L, Carroli G, Abalos E, Widmer M, Amigot S, Nardin JM, et al. Accuracy of diagnostic tests to detect asymptomatic bacteriuria during pregnancy. Obstet Gynecol 2009;113:346-352. https://doi.org/10.1097/AOG.0b013e318194f109
/*ref*/Kovavisarach E, Vichaipruck M, Kanjanahareutai S. Reagent strip testing for antenatal screening and first meaningful of asymptomatic bacteriuria in pregnant women. J Med Assoc Thai 2008;91:1786-1790.
/*ref*/Eigbefoh JO, Isabu P, Okpere E, Abebe J. The diagnostic accuracy of the rapid dipstick test to predict asymptomatic urinary tract infection of pregnancy. J Obstet Gynaecol 2008;28:490-495. https://doi.org/10.1080/01443610802196914
/*ref*/Zaman Z, Borremans A, Verhaegen J, Verbist L, Blanckaert N. Disappointing dipstick screening for urinary tract infection in hospital inpatients. J Clin Pathol 1998;51:471-472. https://doi.org/10.1136/jcp.51.6.471
/*ref*/St John A, Boyd JC, Lowes AJ, Price CP. The use of urinary dipstick tests to exclude urinary tract infection: a systematic review of the literature. Am J Clin Pathol 2006;126:428-436. https://doi.org/10.1309/C69RW1BT7E4QAFPV
/*ref*/Verest LF, van Esch WM, van Ree JW, Stobberingh EE. Management of acute uncomplicated urinary tract infections in general practice in the south of The Netherlands. Br J Gen Pract 2000;50:309-310.
/*ref*/van der Zwet WC, Hessels J, Canbolat F, Deckers MM. Evaluation of the Sysmex UF-1000i(R) urine flow cytometer in the diagnostic work-up of suspected urinary tract infection in a Dutch general hospital. Clin Chem Lab Med 2010;48:1765-1771. https://doi.org/10.1515/CCLM.2010.342
/*ref*/Marschal M, Wienke M, Hoering S, Autenrieth IB, Frick JS. Evaluation of 3 different rapid automated systems for diagnosis of urinary tract infections. Diagn Microbiol Infect Dis 2012;72:125-130. https://doi.org/10.1016/j.diagmicrobio.2011.10.001
/*ref*/Kadkhoda K, Manickam K, Degagne P, Sokolowski P, Pang P, Kontzie N, et al. UF-1000i flow cytometry is an effective screening method for urine specimens. Diagn Microbiol Infect Dis 2011;69:130-136. https://doi.org/10.1016/j.diagmicrobio.2010.09.013
/*ref*/Broeren MA, Bahceci S, Vader HL, Arents NL. Screening for urinary tract infection with the Sysmex UF-1000i urine flow cytometer. J Clin Microbiol 2011;49:1025-1029. https://doi.org/10.1128/JCM.01669-10
/*ref*/Muñoz-Algarra M, Martínez-Ruiz R, Orden-Martínez B. Evaluation of the Sysmex UF-1000i automated system for the diagnosis of urinary tract infection. Enferm Infecc Microbiol Clin 2013;31:29-31. https://doi.org/10.1016/j.eimc.2012.05.017
/*ref*/Brilha S, Proenca H, Cristino JM, Hanscheid T. Use of flow cytometry (Sysmex) UF-100) to screen for positive urine cultures: in search for the ideal cut-off. Clin Chem Lab Med 2010;48:289-292. https://doi.org/10.1515/CCLM.2010.047
/*ref*/Lunn A, Holden S, Boswell T, Watson AR. Automated microscopy, dipsticks and the diagnosis of urinary tract infection. Arch Dis Child 2010;95:193-197. https://doi.org/10.1136/adc.2009.166835
/*ref*/Grosso S, Bruschetta G, De Rosa R, Avolio M, Camporese A. Improving the efficiency and efficacy of pre-analytical and analytical work-flow of urine cultures with urinary flow cytometry. New Microbiol 2008;31:501-505.
/*ref*/Ledru S, Canonne JP. [Comparison of IRIS IQ ELITE and microscopy for urinalysis and evaluation of performance in predicting outcome of urine cultures]. Ann Biol Clin (Paris) 2008;66:555-559.
/*ref*/Tilton RE, Tilton RC. Automated direct antimicrobial susceptibility testing of microscopically screened urine culture. J Clin Microbiol 1980;00:157-161. https://doi.org/10.1128/JCM.11.2.157-161.1980
/*ref*/Pezzlo MT, Tan GL, Peterson EM, De La Maza LM. Screening of urine cultures by three automated systems. J Clin Microbiol 1982 https://doi.org/10.1128/JCM.15.3.468-474.1982
/*ref*/15: 468-474. J Clin Microbiol 1982;15:468-474. https://doi.org/10.1007/BF02261610
/*ref*/Murray PR, Smith TB, McKinney TC, Jr. Clinical evaluation of three urine screening tests. J Clin Microbiol 1987;25:467-470. https://doi.org/10.1128/JCM.25.3.467-470.1987
/*ref*/Winquist AG, Orrico MA, Peterson LR. Evaluation of the cytocentrifuge Gram stain as a screening test for bacteriuria in specimens from specific patient populations. Am J Clin Pathol 1997;108:515-524. https://doi.org/10.1093/ajcp/108.5.515
/*ref*/López JA, Cuartas MC, Molina OL, Restrepo AC, Maya CY, Jaramillo S, et al. Utilidad del citoquímico y la coloración de Gram en muestras de orina en el diagnóstico de las infecciones del tracto urinario en pacientes hospitalizados. Iatreia 2005;18:377-384.
/*ref*/Stamm WE, Hooton TM. Management of urinary tract infections in adults. N Engl J Med 1993;329:1328-1334. https://doi.org/10.1056/NEJM199310283291808
/*ref*/Colgan R, Williams M. Diagnosis and treatment of acute uncomplicated cystitis. Am Fam Physician 2011;84:771-776.
/*ref*/Uncomplicated urinary infection in women: diagnosis. Rev Assoc Med Bras 2011;57:255-258. https://doi.org/10.1016/S0104-4230(11)70054-9
/*ref*/Ross AM. UTI antimicrobial resistance: tricky decisions ahead? Br J Gen Pract 2000;50:612-613.
/*ref*/Sundqvist M, Kahlmeter G. 'Pre-emptive culturing' will improve the chance of 'getting it right' when empirical therapy of urinary tract infections fails. J Antimicrob Chemother 2009;64:227-228. https://doi.org/10.1093/jac/dkp181
/*ref*/Davey P, Steinke D, MacDonald T, Phillips G, Sullivan F. Not so simple cystitis: how should prescribers be supported to make informed decisions about the increasing prevalence of infections caused by drug-resistant bacteria? Br J Gen Pract 2000;50:143-146.
/*ref*/McIsaac WJ, Hunchak CL. Overestimation error and unnecessary antibiotic prescriptions for acute cystitis in adult women. Med Decis Making 2011;31:405-411. https://doi.org/10.1177/0272989X10391671
/*ref*/Butler CC, Hillier S, Roberts Z, Dunstan F, Howard A, Palmer S. Antibiotic-resistant infections in primary care are symptomatic for longer and increase workload: outcomes for patients with E. coli UTIs. Br J Gen Pract 2006;56:686-692.
/*ref*/McNulty CA, Richards J, Livermore DM, Little P, Charlett A, Freeman E, et al. Clinical relevance of laboratory-reported antibiotic resistance in acute uncomplicated urinary tract infection in primary care. J Antimicrob Chemother 2006;58:1000-1008. https://doi.org/10.1093/jac/dkl368
/*ref*/Johnson JD, O'Mara HM, Durtschi HF, Kopjar B. Do urine cultures for urinary tract infections decrease follow-up visits? J Am Board Fam Med 2011;24:647-655. https://doi.org/10.3122/jabfm.2011.06.100299
/*ref*/Oreskovic NM, Sembrano EU. Repeat urine cultures in children who are admitted with urinary tract infections. Pediatrics 2007;119:e325-329. https://doi.org/10.1542/peds.2006-1134
/*ref*/Currie ML, Mitz L, Raasch CS, Greenbaum LA. Follow-up urine cultures and fever in children with urinary tract infection. Arch Pediatr Adolesc Med 2003;157:1237-1240. https://doi.org/10.1001/archpedi.157.12.1237
/*ref*/Pezzlo MT, York MK, Church DL. Urine cultures. In: Clinical Microbiology Procedures Handbook, edited by García LS. Washington, DC: ASM Press, 2010.
/*ref*/Practice parameter: the diagnosis, treatment, and evaluation of the initial urinary tract infection in febrile infants and young children. American Academy of Pediatrics. Committee on Quality Improvement. Subcommittee on Urinary Tract Infection. Pediatrics 1999;103:843-852. https://doi.org/10.1542/peds.103.4.843
/*ref*/Roberts KB. Urinary tract infection: clinical practice guideline for the diagnosis and management of the initial UTI in febrile infants and children 2 to 24 months. Pediatrics 2011;128:595-610. https://doi.org/10.1542/peds.2011-1330
/*ref*/Wingerter S, Bachur R. Risk factors for contamination of catheterized urine specimens in febrile children. Pediatr Emerg Care 2011;27:1-4. https://doi.org/10.1097/PEC.0b013e3182037c20
/*ref*/Mena-Moreno C, Collado-Gómez R, Bellón-Elipe MI. Extracción de muestras de orina. Disponible en http://www.eccpn.aibarra.org/temario/seccion2/capitulo35/capitulo35.htm Consultado en marzo de 2013.
/*ref*/Cabedo Garcia VR, Novoa Gomez C, Tirado Balaguer MD, Rodriguez Morquecho N, Rodriguez Bailo MT, Sola Sandtner A. ¿Es importante la técnica de recogida de la orina para evitar la contaminación de las muestras? Aten Primaria 2004;33:140-144. https://doi.org/10.1016/S0212-6567(04)79374-9
/*ref*/Holliday G, Strike PW, Masterton RG. Perineal cleansing and midstream urine specimens in ambulatory women. J Hosp Infect 1991;18:71-75. https://doi.org/10.1016/0195-6701(91)90096-Q
/*ref*/Blake DR, Doherty LF. Effect of perineal cleansing on contamination rate of mid-stream urine culture. J Pediatr Adolesc Gynecol 2006;19:31-34. https://doi.org/10.1016/j.jpag.2005.11.003
/*ref*/Leisure MK, Dudley SM, Donowitz LG. Does a clean-catch urine sample reduce bacterial contamination? N Engl J Med 1993;328:289-290. https://doi.org/10.1056/NEJM199301283280420
/*ref*/Schneeberger C, van den Heuvel ER, Erwich JJ, Stolk RP, Visser CE, Geerlings SE. Contamination rates of three urine-sampling methods to assess bacteriuria in pregnant women. Obstet Gynecol 2013;121:299-305. https://doi.org/10.1097/AOG.0b013e31827e8cfe
/*ref*/Baerheim A, Digranes A, Hunskaar S, Laerum E. Bacteriological findings in urine specimens from women. Association with urinary tract symptoms and sampling methods. Scand J Urol Nephrol 1991;25:125-127. https://doi.org/10.3109/00365599109024546
/*ref*/Baerheim A, Digranes A, Hunskaar S. Evaluation of urine sampling technique: bacterial contamination of samples from women students. Br J Gen Pract 1992;42:241-243.
/*ref*/Immergut MA, Gilbert EC, Frensilli FJ, Goble M. The myth of the clean catch urine specimen. Urology 1981;17:339-340. https://doi.org/10.1016/0090-4295(81)90259-4
/*ref*/Lifshitz E, Kramer L. Outpatient urine culture: does collection technique matter? Arch Intern Med 2000;160:2537-2540. https://doi.org/10.1001/archinte.160.16.2537
/*ref*/Grahn D, Norman DC, White ML, Cantrell M, Yoshikawa TT. Validity of urinary catheter specimen for diagnosis of urinary tract infection in the elderly. Arch Intern Med 1985;145:1858-1860. https://doi.org/10.1001/archinte.1985.00360100120020
/*ref*/Al-Orifi F, McGillivray D, Tange S, Kramer MS. Urine culture from bag specimens in young children: are the risks too high? J Pediatr 2000;137:221-226. https://doi.org/10.1067/mpd.2000.107466
/*ref*/Li PS, Ma LC, Wong SN. Is bag urine culture useful in monitoring urinary tract infection in infants? J Paediatr Child Health 2002;38:377-381. https://doi.org/10.1046/j.1440-1754.2002.00010.x
/*ref*/Alam MT, Coulter JB, Pacheco J, Correia JB, Ribeiro MG, Coelho MF, et al. Comparison of urine contamination rates using three different methods of collection: clean-catch, cotton wool pad and urine bag. Ann Trop Paediatr 2005;25:29-34. https://doi.org/10.1179/146532805X23326
/*ref*/Schlager TA, Hendley JO, Dudley SM, Hayden GF, Lohr JA. Explanation for false-positive urine cultures obtained by bag technique. Arch Pediatr Adolesc Med 1995;149:170-173. https://doi.org/10.1001/archpedi.1995.02170140052007
/*ref*/Hindman R, Tronic B, Bartlett R. Effect of delay on culture of urine. J Clin Microbiol 1976;4:102-103.
/*ref*/Gillespie T, Fewster J, Masterton RG. The effect of specimen processing delay on borate urine preservation. J Clin Pathol 1999;52:95-98. https://doi.org/10.1136/jcp.52.2.95
/*ref*/Chaux C, Crepy M, Xueref S, Roure C, Gille Y, Freydiere AM. Comparison of three chromogenic agar plates for isolation and identification of urinary tract pathogens. Clin Microbiol Infect 2002;8:641-645. https://doi.org/10.1046/j.1469-0691.2002.00433.x
/*ref*/Scarparo C, Piccoli P, Ricordi P, Scagnelli M. Comparative evaluation of two commercial chromogenic media for detection and presumptive identification of urinary tract pathogens. Eur J Clin Microbiol Infect Dis 2002;21:283-289. https://doi.org/10.1007/s10096-002-0718-0
/*ref*/Aspevall O, Osterman B, Dittmer R, Sten L, Lindback E, Forsum U. Performance of four chromogenic urine culture media after one or two days of incubation compared with reference media. J Clin Microbiol 2002;40:1500-1503. https://doi.org/10.1128/JCM.40.4.1500-1503.2002
/*ref*/Baker M, Cheetham P, Shing J, Yau N. Chromogenic urinary tract infection medium: evaluation and introduction for routine urine culture in a large clinical microbiology laboratory. Br J Biomed Sci 2001;58:207-211.
/*ref*/Yagupsky P, Rider M, Peled N. Clinical evaluation of a novel chromogenic agar dipslide for diagnosis of urinary tract infections. Eur J Clin Microbiol Infect Dis 2000;19:694-698. https://doi.org/10.1007/s100960000345
/*ref*/Carricajo A, Boiste S, Thore J, Aubert G, Gille Y, Freydiere AM. Comparative evaluation of five chromogenic media for detection, enumeration and identification of urinary tract pathogens. Eur J Clin Microbiol Infect Dis 1999;18:796-803. https://doi.org/10.1007/s100960050403
/*ref*/Houang ET, Tam PC, Lui SL, Cheng AF. The use of CHROMagar Orientation as a primary isolation medium with presumptive identification for the routine screening of urine specimens. APMIS 1999;107:859-862. https://doi.org/10.1111/j.1699-0463.1999.tb01483.x
/*ref*/D'Souza HA, Campbell M, Baron EJ. Practical bench comparison of BBL CHROMagar Orientation and standard two-plate media for urine cultures. J Clin Microbiol 2004;42:60-64. https://doi.org/10.1128/JCM.42.1.60-64.2004
/*ref*/Ciragil P, Gul M, Aral M, Ekerbicer H. Evaluation of a new chromogenic medium for isolation and identification of common urinary tract pathogens. Eur J Clin Microbiol Infect Dis 2006;25:108-111. https://doi.org/10.1007/s10096-006-0103-5
/*ref*/Manickam K, Karlowsky JA, Adam H, Lagace-Wiens PR, Rendina A, Pang P, et al. CHROMagar Orientation Medium Reduces Urine Culture Workload. J Clin Microbiol 2013;51:1179-1183. https://doi.org/10.1128/JCM.02877-12
/*ref*/Munoz-Davila MJ, Roig M, Yague G, Blazquez A, Salvador C, Segovia M. Comparative evaluation of Vitek 2 identification and susceptibility testing of urinary tract pathogens directly and isolated from chromogenic media. Eur J Clin Microbiol Infect Dis 2013. https://doi.org/10.1007/s10096-012-1806-4
/*ref*/Aliskan HE, Colakoglu S, Turunc T, Demiroglu YZ. [Evaluation of the ChromID ESBL agar for the detection of ESBL-positive Enterobacteriaceae and vancomycin-resistant enterococcus isolates from urine cultures]. Mikrobiyol Bul 2012;46:17-25.
/*ref*/Joho KL, Soliman H, Weinstein MP. Comparison of one-day versus two-day incubation of urine cultures. Diagn Microbiol Infect Dis 1995;21:55-56. https://doi.org/10.1016/0732-8893(94)00115-D
/*ref*/Murray P, Traynor P, Hopson D. Evaluation of microbiological processing of urine specimens: comparison of overnight versus two-day incubation. J Clin Microbiol 1992;30:1600-1601. https://doi.org/10.1128/JCM.30.6.1600-1601.1992
/*ref*/Cermak P, Ptakova M, Kubele J, Cermakova R, Jedlickova A. [Detection of urinary tract infection using Uro-Quick system and quantitative dilution method]. Klin Mikrobiol Infekc Lek 2009;15:166-170.
/*ref*/Velasco D, Gil E, García P, Guerrero A. Eficacia de dos métodos semiautomáticos para la exclusión de bacteriuria. Enferm Infecc Microbiol Clin 2002;20:22-24. https://doi.org/10.1016/S0213-005X(02)72726-2
/*ref*/Ilki A, Bekdemir P, Ulger N, Soyletir G. Rapid reporting of urine culture results: impact of the uro-quick screening system. New Microbiol 2010;33:147-153.
/*ref*/Graham JC, Galloway A. The laboratory diagnosis of urinary tract infection. J Clin Pathol 2001;54:911-919. https://doi.org/10.1136/jcp.54.12.911
/*ref*/Bank S, Jensen A, Hansen TM, Soby KM, Prag J. Actinobaculum schaalii, a common uropathogen in elderly patients, Denmark. Emerg Infect Dis 2010;16:76-80. https://doi.org/10.3201/eid1601.090761
/*ref*/Wood EG, Dillon HC, Jr. A prospective study of group B streptococcal bacteriuria in pregnancy. Am J Obstet Gynecol 1981;140:515-520. https://doi.org/10.1016/0002-9378(81)90226-X
/*ref*/Centers for Disease Control and Prevention. Prevention of perinatal group B streptococcal disease. Revised guidelines from CDC. MMWR Recommend Rep 2010; 50(RR-10): 1-32.
/*ref*/Kauffman CA. Candiduria. Clin Infect Dis 2005;41 Suppl 6:S371-376. https://doi.org/10.1086/430918
/*ref*/Lundstrom T, Sobel J. Nosocomial candiduria: a review. Clin Infect Dis 2001;32:1602-1607. https://doi.org/10.1086/320531
/*ref*/McLeod D, Kljakovic M. What do general practitioners do when patients present with symptoms indicative of urinary tract infections? N Z Med J 1998;111:189-191.
/*ref*/Owens RC, Jr. Antimicrobial stewardship: concepts and strategies in the 21st century. Diagn Microbiol Infect Dis 2008;61:110-128. https://doi.org/10.1016/j.diagmicrobio.2008.02.012
/*ref*/CLSI. M100-S23. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Third Informational Supplement. Wayne: Clinical and Laboratory Standards Institute, 2013.
/*ref*/Breteler KB, Rentenaar RJ, Verkaart G, Sturm PD. Performance and clinical significance of direct antimicrobial susceptibility testing on urine from hospitalized patients. Scand J Infect Dis 2011;43:771-776. https://doi.org/10.3109/00365548.2011.588609
/*ref*/Johnson JR, Tiu FS, Stamm WE. Direct antimicrobial susceptibility testing for acute urinary tract infections in women. J Clin Microbiol 1995;33:2316-2323. https://doi.org/10.1128/JCM.33.9.2316-2323.1995
 

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