The Effect of Vitamin C Addition on Epigallocatechin Gallate (EGCG) Stability in Green Tea Solution

Jurnal Farmasi dan Ilmu Kefarmasian Indonesia

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Title The Effect of Vitamin C Addition on Epigallocatechin Gallate (EGCG) Stability in Green Tea Solution
 
Creator Rahman, Alief Putriana
Purwanto, Djoko Agus
Isnaeni, Isnaeni
 
Subject
EGCG, vitamin C, stability, green tea, TLC
 
Description Background: Epigallocatechin gallate (EGCG) is the most abundant green tea catechin with a powerful antioxidant effect to prevent cancer cells. EGCG in green tea solution is highly susceptible to degradation, this it is urgent to  increase the stability of EGCG by vitamin C addition. Vitamin C can regenerate radical EGCG to be normal EGCG. Objective: This research aim was to determine percent of decreased level of EGCG before and after vitamin C addition. Methods: This paper was focused on enhancing the stability of EGCG by 1 mg (GTVC1), 1.5 mg (GTVC2), 2 mg (GTVC3), 2.5 mg (GTVC4) and 3 mg (GTVC5) of vitamin C addition to 10 g/L of green tea solution concentration. Evaluations of EGCG were conducted at 0 days, 1 day, 2 days, 3 days, and 4 days of storage time. EGCG was analyzed using thin layer chromatography (TLC) densitometry methods. The stability of EGCG was determined by % of decreased EGCG. Results: Percent of loss of EGCG in GT, GTVC1, GTVC2, GTVC3, GTVC4 and GTVC5 after 4 days storage were 19.93%, 10.89%, 21.08%, 18.18%, 28.56%, and 9.76%, respectively. Conclusion: This study showed that in 4 days storage, the decreased level of EGCG in green tea solution with 3 mg of vitamin C addition (GTVC5) was 9.76% which was smaller than green tea solution without vitamin C addition (GT) which EGCG decreasing 19.93%.
 
Publisher Fakultas Farmasi Universitas Airlangga
 
Contributor
 
Date 2020-03-04
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier https://e-journal.unair.ac.id/JFIKI/article/view/16495
10.20473/jfiki.v6i22019.62-68
 
Source JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA; Vol 6, No 2 (2019): JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA; 62-68
2580-8303
2406-9388
 
Language eng
 
Relation https://e-journal.unair.ac.id/JFIKI/article/view/16495/9834
https://e-journal.unair.ac.id/JFIKI/article/downloadSuppFile/16495/4008
 
Rights Copyright (c) 2020 JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA
http://creativecommons.org/licenses/by-nc-sa/4.0
 

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