Boosting Sperm Count Using Red Ginger in Mice Induced by Paraquat Dichloride (1.1-dimethyl-4.4 bipyridinium)

Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati (J-BEKH)

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Title Boosting Sperm Count Using Red Ginger in Mice Induced by Paraquat Dichloride (1.1-dimethyl-4.4 bipyridinium)
 
Creator Umairoh, Siti; Jurusan Biologi FMIPA Unila
Sutyarso, Sutyarso; Jurusan Biologi FMIPA Unila
Kanedi, M.; Jurusan Biologi FMIPA Unila
Busman, Hendri; Jurusan Biologi FMIPA Unila
 
Subject Infertility; Red Ginger; spermatogenic cells; Mus musculus L.; Paraquat dichloride
 
Description Paraquat dichloride (1.1'-dimethyl-4.4'-bipyridinium dichloride) was commonly herbicide used by most farmers in Indonesia. It raises herbicide-free radicals and affects male reproductive organs. It caused infertility such as a decrease in the number of spermatogenic cells. Fortunately, red ginger has capable of dealing with infertility problems. This study aims to see whether the ethanol extract of red ginger can increase the number of spermatocyte and spermatid cells induced by paraquat dichloride. This study uses a completely randomized design with 24 male mice were divided into six treatment groups with four replications. Group K as a control (H2O), J (Ginger 18 mg / ml), Pq (Paraquat 20mg / BB), P1 (Pq 20 mg / BB + EEJM 6 mg / ml), P2 (Paraquat 20mg / BB + EEJM 12 mg / ml) and P3 (Paraquat 20mg / BB + EEJM 18 mg / ml). Paraquat is given 2 times a week for 21 days, while the ethanol extract of red ginger added for 35 days. The number of cells spermatocyte and spermatid cells of male mice, analysis of variance (ANOVA), and Least Significant Difference Test (BNT) level of 5% observed as the parameter. The results showed that ethanol extract of red ginger 6, 12 and 18 mg/ml increased the number of spermatocyte and spermatid cells of male mice induced by paraquat dichloride.
 
Publisher Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Lampung
 
Contributor
 
Date 2019-12-19
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
 
Format application/pdf
 
Identifier http://jurnal.fmipa.unila.ac.id/jbekh/article/view/2373
10.23960/j-bekh.v6i2.2373
 
Source Jurnal Ilmiah Biologi Ekperimen dan Keanekaragaman Hayati (J-BEKH); Vol 6, No 2 (2019); 1-7
Jurnal Ilmiah Biologi Eksperimen dan Keanekaragaman Hayati; Vol 6, No 2 (2019); 1-7
2686-200X
2338-4344
10.23960/j-bekh.v6i2
 
Language eng
 
Relation http://jurnal.fmipa.unila.ac.id/jbekh/article/view/2373/1717
 
Rights Authors who publish with this journal agree to the following terms:Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).
 

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