Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study

International Journal of Current Research in Physiology and Pharmacology (IJCRPP)

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Field Value
 
Title Evaluating serum C-reactive protein level in patients with chronic obstructive pulmonary disease – A cross-sectional study
 
Creator M, Karthika
Bhardwaj, Prakash Chandra
Sharma, Laimayum Amarnath
Sharma, Laimayum Amarnath
Kanan, W
Singh, W Asoka
 
Description Abstract
Patients with the chronic obstructive pulmonary disease have ongoing systemic inflammation, which can be assessed by measuring serum  C- reactive protein.
Objective: To explore whether CRP could be used as an independent predictor of disease outcome in COPD.
Methods: A cross-sectional study was conducted among 50 COPD patients attending Respiratory Medicine outpatient services in the Regional Institute of Medical Sciences (RIMS), Imphal from January 2015 to September 2016. Patients aged 18-67 were included in the study after obtaining Ethical approval from the Research Ethics Board, RIMS, Imphal. Computerized Spirometer Helios 401 was the instrument used to measure lung volumes and capacities. BeneSpheraTM CRP Latex Slide test kit was used to estimate serum c-reactive protein.
Results and observation: The present study was conducted on fifty COPD patients in which serum CRP level showed positive correlation with COPD (p=0.002) but serum CRP level with spirometric parameters showed significant negative correlation;FEV1 (r=-0.451, p=0.001), FEV1/FVC (r=-0.617, p<0.001) and PEFR (r=-0.398, p=0.004).
Conclusion: In our study, we found an association between serum CRP level and severity of COPD and Plasma CRP may be used as a marker of prognosis in COPD as the small increase is associated with poorer prognosis in COPD.
Keywords: CRP; Chronic obstructive pulmonary disease (COPD); Imphal.
 
Publisher Sumathi Publications
 
Date 2019-10-31
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format text/html
application/pdf
 
Identifier https://sumathipublications.com/index.php/ijcrpp/article/view/300
10.31878/ijcrpp.2019.34.1
 
Source International Journal of Current Research in Physiology and Pharmacology (IJCRPP); Volume 3, Issue 4; 2019; 1-4
2523-6709
2523-6695
 
Language eng
 
Relation https://sumathipublications.com/index.php/ijcrpp/article/view/300/340
https://sumathipublications.com/index.php/ijcrpp/article/view/300/342
 
Rights Copyright (c) 2019 Karthika M, Prakash Chandra Bhardwaj, Laimayum Amarnath Sharma, Laimayum Amarnath Sharma, W Kanan, W Asoka Singh
http://creativecommons.org/licenses/by-nc-sa/4.0
 

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