HELLP Syndrome, a severe form of preeclampsia: a comparative study of clinical and laboratorial parameters

American Journal of Experimental and Clinical Research

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Field Value
 
Title HELLP Syndrome, a severe form of preeclampsia: a comparative study of clinical and laboratorial parameters
 
Creator Campos, Ana Correia
 
Subject Medicine; Obstetrics and Gynecology
Preeclampsia, thrombocytopenia, maternal and perinatal morbidity, HELLP syndrome
RG551-591
 
Description The objective of this study was to compare clinical, laboratorial, maternal and perinatal results between HELLP Syndrome and severe Preeclampsia. An observational study comparing women with HELLP Syndrome (n=71) to women with severe preeclampsia (n=253) was done. The authors analyzed the early course of the pathologies and the outcomes in both groups. HELLP syndrome occurred in 28% of all the cases and was more frequent at gestational age before 32 weeks (n=39 – 55%) than severe preeclampsia (n=108 - 42%), with more newborns weighting less than 1500g (27 – 38.6% vs 65 – 25.6%; p=0.036). Thrombocytopenia below 100 000/µL (aOR, 2.14; 95% CI, 1.49 – 3.06) and LDH>1 000 UI/L (aOR: 5.17; 95% CI 2.19 – 12.16) were risk factors for HELLP. Maternal morbidity (eclampsia, abruptio placentae, and acute renal failure) was similar in both cohorts; eight stillbirths (6 in severe preeclampsia and 2 in HELLP Syndrome) occurred. There were no maternal deaths. In conclusion, in this study the authors confirmed that HELLP Syndrome is a severe form of preeclampsia with an earlier presentation in pregnancy, worst laboratorial findings and more prematurity rates.
 
Publisher American Journal of Experimental & Clinical Research
 
Contributor No funding
 
Date 2016-07-04
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
Peer-reviewed Article
Clinical Medicine
 
Format application/pdf
 
Identifier http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/77
 
Source American Journal of Experimental and Clinical Research; Vol 3, No 3 (2016); 170-174
2330-9245
2330-9237
 
Language eng
 
Relation http://journals.sfu.ca/ajecr/index.php/ajecr/article/view/77/163
 
Rights Copyright (c) 2016 American Journal of Experimental and Clinical Research
 

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