The BMPR2, ALK1 and ENG Genes Mutation in Congenital Heart DiseaseAssociated Pulmonary Artery Hypertension

ACI (Acta Cardiologia Indonesiana)

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Field Value
 
Title The BMPR2, ALK1 and ENG Genes Mutation in Congenital Heart DiseaseAssociated Pulmonary Artery Hypertension
 
Creator Hartopo, Anggoro Budi
Anggrahini, Dyah Wulan
Emoto, Noriaki
Dinarti, Lucia Kris
 
Subject gene mutation; pulmonary artery hypertension; congenital heart disease– associated PAH
 
Description The gene mutation is one of the background underlie the pathogenesis of pulmonary artery hypertension (PAH). Several genes have been recognized to be responsible for the development of PAH. The mutation in transforming growth factor-β (TGF-β) pathway is considered to be major genotype background in heritable PAH. The genetic mutation in bone morphogenetic protein receptor-2 (BMPR2), activin receptor-like kinase 1 (ALK-1) and endoglin (ENG) are known to cause heritable PAH. In congenital heart disease–associated PAH (CHDAPAH), their mutation are also presence.
 
Publisher Faculty of Medicine, Public Health and Nursing Universitas Gadjah Mada
 
Contributor
 
Date 2019-10-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier https://jurnal.ugm.ac.id/jaci/article/view/50222
10.22146/aci.50222
 
Source ACI (Acta Cardiologia Indonesiana); Vol 5, No 2 (2019); 145-149
2579-4345
2460-5700
 
Language eng
 
Relation https://jurnal.ugm.ac.id/jaci/article/view/50222/25705
 
Rights Copyright (c) 2019 Anggoro Budi Hartopo, Dyah Wulan Anggrahini, Noriaki Emoto, Lucia Kris Dinarti
http://creativecommons.org/licenses/by-sa/4.0
 

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