EFFECT OF AFLATOXIN M1, "A HYDROXYLATED METABOLITE OF B1" ON SPERM CELL QUALITY OF ADULT MALE WISTAR RATS.

International Journal of Current Research in Physiology and Pharmacology (IJCRPP)

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Field Value
 
Title EFFECT OF AFLATOXIN M1, "A HYDROXYLATED METABOLITE OF B1" ON SPERM CELL QUALITY OF ADULT MALE WISTAR RATS.
 
Creator Nnanna, Ibeh Isaiah
Ekrakene, Taidi
MO, Okungbowa
Florence, Otabor
Terry, Omorodion Nosa
 
Description The effect of aflatoxin on reproductive health takes a systematic approach as it indicates that a significant number of people living in the third world regions are exposed to these toxins due to the poor storage of grains. To expose the effects of aflatoxin M1 a hydroxylated metabolite of aflatoxin M1 Twenty four Adult male Wister rats were acclimatized and broken down into four groups, Test Group one (Two weeks exposure), Group Two ( four weeks exposure), Group Three ( Six weeks exposure) and Group Four ( Control Group). The Test Group 1, 2 and 3 were orally administered 7.2g/kg (LD50) of Aflatoxin M1 for the desired weeks of exposure and the sperm cell quality was assessed to determine the effect of Aflatoxin M1 on sperm cell quality in Adult male wister rat. The predetermined level of sperm cell quality is its ability to be motile as the motility of the sperm cell determines its viability. Group three had the highest presence of sluggishly immotile cells with very low progressive motility, followed by group, two and one, 37.5+ 9.97, 55.00+9.91, and 71.67+3.07 as against the control groups 85.8+2.17 with the highest significance at the group three which showed an extended exposure of aflatoxin m1 (p=0.05). This study links infertility and aflatoxin consumption, as the higher the doses the more spermatotoxicity is built which invariably could lead to sterility and azoospermia.
 
Publisher Sumathi Publications
 
Date 2019-04-25
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier https://www.sumathipublications.com/index.php/ijcrpp/article/view/250
10.31878/ijcrpp.2019.32.2
 
Source International Journal of Current Research in Physiology and Pharmacology (IJCRPP); Volume 3, Issue 2; 2019; 7-12
2523-6709
2523-6695
 
Language eng
 
Relation https://www.sumathipublications.com/index.php/ijcrpp/article/view/250/307
 
Rights Copyright (c) 2019 Ibeh Isaiah Nnanna, Taidi Ekrakene, Okungbowa MO, Otabor Florence, Omorodion Nosa Terry
http://creativecommons.org/licenses/by-nc-sa/4.0
 

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