SYNTHESIS AND BIOLOGICAL ACTIVITIES EVALUATION OF NEW SUBSTITUTED 1,2,4,8-TETRAAZASPIRO[4.5]DEC-2-ENES

Journal of Applied Chemical Science International

View Publication Info
 
 
Field Value
 
Title SYNTHESIS AND BIOLOGICAL ACTIVITIES EVALUATION OF NEW SUBSTITUTED 1,2,4,8-TETRAAZASPIRO[4.5]DEC-2-ENES
 
Creator DALLOUL, HANY M.
EL-NWAIRY, KHALED A.
SHORAFA, ALI Z.
ABU SAMAHA, AHMED S.
 
Description A new series of 1,2,4,8-tetraazaspiro[4.5]dec-2-enes containing 1,2,4-triazole, piperidine and sulfonamide moieties have been synthesized from the reaction of 4-piperidone benzoylhydrazones having 1-methyl, 1-benzyl, and 1-isopropyl groups with appropriate nitrilimines. The microanalysis and spectral data (IR, 1H NMR, 13C NMR and MS) of the synthesized compounds are in full agreement with their molecular structure. The microbial features of the synthesized compounds were studied by a known method. Some of titled compounds exhibited significant antimicrobial activity on several strains of microbes.
 
Publisher International Knowledge Press
 
Date 2018-02-28
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier http://www.ikprress.org/index.php/JACSI/article/view/4126
 
Source Journal of Applied Chemical Science International; 2017 - Volume 8 [Issue 4]; 144-152
2395-3713
 
Language eng
 
Relation http://www.ikprress.org/index.php/JACSI/article/view/4126/3899
 
Rights Copyright (c) 2018 © Copyright International Knowledge Press. All rights reserved.
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library