CHEMICAL AND MINERALOGICAL CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SENEGAL’S MUDS

Journal of Applied Chemical Science International

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Field Value
 
Title CHEMICAL AND MINERALOGICAL CHARACTERIZATION AND ANTI-INFLAMMATORY ACTIVITY EVALUATION OF SENEGAL’S MUDS
 
Creator GUEYE, ROKHAYA SYLLA
SY, AWA NDIAYE
BADIANE, INSA
DIOP, MOUHAMADOU BASSIR
SALL, CHEIKH
BALDE, MAMADOU
SENE, MADIEYE
NDAO, YOUSSOU
DIEDHIOU, ADAMA
SY, GUATA YORO
SECK, MATAR
FALL, DJIBRIL
WELE, ALASSANE
 
Description Clays have been use in therapeutics for a long time and proliferation of thermal mud centers testifies to its effectiveness. In our work, anti-inflammatory activity of Ziguinchor mangrove sludge and Mbodiène attapulgite was evaluated, after a chemical and mineralogical characterization. Results obtained showed for mangrove mud multiple components with mainly varying contents in sodium, aluminum, chlorine, silicon and iron. Attapulgite was predominantly composed of silicon 55.15%, magnesium 13.8%, calcium 11.11%, iron 8.3% and aluminum 7.78%. The cation exchange capacity evaluated with the cobaltihexamine ion was 95 meq / 100 g for Attapulgite versus 6.85 meq / 100 g for the mangrove mud. Mineralogical analysis has shown that mangrove mud consists essentially of kaolinite and palygorskite is the dominant mineral of attapulgite with quartz, crystals of ankerites, dolomites. Anti-inflammatory activity evaluation showed a percentage of inhibition of edema induced in croton oil from 25.23% for attapulgite, to 28.34% for Ziguinchor mud, against 52, 26% for Voltaren Emulgel® as reference. These results predict a good way of additional treatment at lower cost for pathologies such as osteoarthritis.
 
Publisher International Knowledge Press
 
Date 2017-11-22
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier http://www.ikprress.org/index.php/JACSI/article/view/3819
 
Source Journal of Applied Chemical Science International; 2017 - Volume 8 [Issue 3]; 95-105
2395-3713
 
Language eng
 
Relation http://www.ikprress.org/index.php/JACSI/article/view/3819/3594
 
Rights Copyright (c) 2017 Copyright @ International Knowledge Press. All rights reserved
 

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