Risk of small for gestational age babies in preterm delivery due to pregnancy-induced hypertension

Medical Journal of Indonesia

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Field Value
 
Title Risk of small for gestational age babies in preterm delivery due to pregnancy-induced hypertension
 
Creator Irwinda, Rima; Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
Santoso, Budi Iman; Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
Surya, Raymond; Department of Obstetrics and Gynecology, Faculty of Medicine Universitas Indonesia, Cipto Mangunkusumo Hospital, Jakarta
Nembo, Lidia Firmiaty; Department of Obstetrics and Gynecology, Ende Hospital, East Nusa Tenggara, Kupang
 
Subject fetal growth; pregnancy-induced hypertension; preterm delivery; small for gestational age
 
Description BACKGROUND Pregnancy-induced hypertension (PIH) causes high maternal morbidity and mortality worldwide. This study aims to assess the impact of PIH on fetal growth according to gestational age in preterm deliveries.METHODS A prospective cohort study using secondary data was undertaken in Ende District, East Nusa Tenggara, Indonesia from September 2014 to August 2015. The t-test was performed to compare mean birth weight based on gestational week between normotensive and PIH women, continued by linear regression. The chi-square or Fisher exact test was also conducted to determine the probability of birthing small for the gestational age (SGA) and large for gestational age (LGA) babies between normotensive and PIH women.RESULTS A total of 1,673 deliveries were recorded in Ende Hospital over the 1-year study period, among which 182 cases involved preterm births. The PIH group had lower birth weight than normotensive women at each gestational age starting from 32–35 weeks (p=0.004; 95% CI 150.84–771.36). Normotensive women at gestational ages of 32 (p=0.05; 95% CI 0.01–0.83), 34 (p=0.37; 95% CI 0.01–4.12), and 36 (p=0.31; 95% CI 0.02–2.95) weeks had a lower risk of birthing SGA babies than PIH women; LGA babies were recorded at gestational ages of 33 (p=1.00; 95% CI 0.07–37.73) and 35 (p=0.31; 95% CI 0.34–63.07) weeks.CONCLUSIONS Poor perfusion of the uteroplacental is one of the reasons behind intrauterine growth restriction, which results in SGA babies born to PIH women.
 
Publisher Faculty of Medicine Universitas Indonesia
 
Contributor
 
Date 2019-05-08
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion

 
Format application/pdf
 
Identifier http://mji.ui.ac.id/journal/index.php/mji/article/view/1795
10.13181/mji.v28i1.1795
 
Source Medical Journal of Indonesia; Vol 28, No 1 (2019): March; 57-62
2252-8083
0853-1773
10.13181/mji.v28i1
 
Language eng
 
Relation http://mji.ui.ac.id/journal/index.php/mji/article/view/1795/1312
 
Rights Copyright (c) 2019 Budi Iman Santoso, Rima Irwinda, Raymond Surya, Lidia Firmiaty Nembo
http://creativecommons.org/licenses/by-nc/4.0
 

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