INVASIVE CERVICAL CANCER IN IBADAN: SOCIO-SEXUAL CHARACTERISTICS, CLINICAL STAGE AT PRESENTATION, HISTOPATHOLOGY DISTRIBUTIONS AND HIV STATUS

African Journal of Infectious Diseases (AJID)

View Publication Info
 
 
Field Value
 
Title INVASIVE CERVICAL CANCER IN IBADAN: SOCIO-SEXUAL CHARACTERISTICS, CLINICAL STAGE AT PRESENTATION, HISTOPATHOLOGY DISTRIBUTIONS AND HIV STATUS
 
Creator Awolude, Olutosin A.
Oyerinde, Sunday O.
 
Description Background: Human Papillomavirus (HPV) infection persistence is the necessary but not sufficient cause of invasive
cervical cancer (ICC). The effects of Human Immunodeficiency Virus (HIV) co-infection have been well documented.
The purpose of this study was to describe our experience on the clinico-pathological characteristics of patients with
cervical cancer and HIV status at a tertiary Hospital in Nigeria.
Materials and Methods: This was a descriptive study among ICC patients presenting for clinical staging and biopsy
for histological diagnosis at the Obstetrics and Gynaecology outpatient theatre of our hospital between January 2009
and February 2011
Results: Sixteen (6.8%) of the 248 patients with histologically confirmed ICC in this study were HIV positive. The
mean age of all the participants was 55.4 (SD±10.2) years with the HIV positive patients’ younger than the HIVnegative
and those that declined HIV testing. Coitarche was at lower age (18 [SD±4.4] vs 22[SD±3.4] years vs
24.5[SD±4.4], respectively). The modal lifetime sexual partners were four, one and two, respectively. Clinically, more
HIV positive patients, presented at advanced stage of ≥ 2B. Also, the adenocarcinoma histological variant was slightly
more among the HIV positive patients.
Conclusion: HIV seemed relatively common among ICC patients and they presented at lower ages, at more advanced
stages, earlier coitarche and more lifetime sexual partners. The proportion of adenocarcinoma histological types was
slightly higher among the HIV positive patients compared with seronegative patients and those with unknown HIV
status. Larger studies to substantiate these findings and ICC-HIV causal relationship are required.
 
Publisher African Traditional Medicine Supporters Initiative (ATHMSI), 7, Road 1, Otunmaiye Square
 
Date 2018-12-12
 
Type info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
 
Format application/pdf
 
Identifier http://journals.athmsi.org/index.php/AJID/article/view/5223
10.21010/ajid.v13i1.4
 
Source African Journal of Infectious Diseases (AJID); Vol 13 No 1 (2019); 32-38
2505-0419
2006-0165
 
Language eng
 
Relation http://journals.athmsi.org/index.php/AJID/article/view/5223/3166
 
Rights Copyright (c) 2018 Olutosin A. Awolude, Sunday O. Oyerinde
http://creativecommons.org/licenses/by/4.0
 

Contact Us

The PKP Index is an initiative of the Public Knowledge Project.

For PKP Publishing Services please use the PKP|PS contact form.

For support with PKP software we encourage users to consult our wiki for documentation and search our support forums.

For any other correspondence feel free to contact us using the PKP contact form.

Find Us

Twitter

Copyright © 2015-2018 Simon Fraser University Library